Gene expression networks in the Drosophila Genetic Reference Panel.
Sign Up to like & getrecommendations! Published in 2020 at "Genome research"
DOI: 10.1101/gr.257592.119
Abstract: A major challenge in modern biology is to understand how naturally occurring variation in DNA sequences affects complex organismal traits through networks of intermediate molecular phenotypes. This question is best addressed in a genetic mapping… read more here.
Keywords: reference panel; drosophila genetic; gene expression; genetic reference ... See more keywords
Variation in Host Resistance to Blastomyces dermatitidis: Potential Use of Genetic Reference Panels and Advances in Immunophenotyping of Diverse Mouse Strains
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DOI: 10.1128/mbio.03400-21
Abstract: Host genetic variation significantly impacts vulnerability to infectious diseases. While host variation in susceptibility to fungal infection with dimorphic fungi has long been recognized, genes that underpin this variation are poorly understood. ABSTRACT Host genetic… read more here.
Keywords: reference panels; resistance; infection; host ... See more keywords
Echocardiography phenotyping in murine genetic reference population of BXD strains reveals significant eQTLs associated with cardiac function and morphology.
Sign Up to like & getrecommendations! Published in 2022 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00120.2022
Abstract: BACKGROUND The genetic reference population of recombinant inbred BXD mice has been derived from crosses between C57BL/6J and DBA/2J strains. The DBA/2J parent exhibits cardiomyopathy phenotypes, while C57BL/6J has normal heart. BXD mice are sequenced… read more here.
Keywords: bxd strains; significant eqtls; genetic reference; reference population ... See more keywords