Dynamic Analysis of the Time-Delayed Genetic Regulatory Network Between Two Auto-Regulated and Mutually Inhibitory Genes
Sign Up to like & getrecommendations! Published in 2020 at "Bulletin of Mathematical Biology"
DOI: 10.1007/s11538-020-00722-1
Abstract: Time delays play important roles in genetic regulatory networks. In this paper, a gene regulatory network model with time delays and mutual inhibition is considered, where time delays are regarded as bifurcation parameters. In the… read more here.
Keywords: regulatory network; time delayed; time; genetic regulatory ... See more keywords
Stability and Hopf bifurcation of fractional genetic regulatory networks with diffusion
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DOI: 10.1016/j.ifacol.2017.08.1973
Abstract: Abstract In this paper, a fractional genetic regulatory network with diffusion is proposed and several dynamic behaviors are investigated. The local stability and instability without and with diffusion are studied, respectively. The criteria for the… read more here.
Keywords: fractional genetic; diffusion; stability hopf; genetic regulatory ... See more keywords
Stochastic stabilization of genetic regulatory networks
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DOI: 10.1016/j.neucom.2017.05.027
Abstract: Abstract This paper is concerned with the stochastic stabilization for genetic regulatory networks. Based on the Lyapunov stability theory in combination with certain convex algorithm, we obtain the sufficient condition under which the unstable genetic… read more here.
Keywords: regulatory networks; stochastic stabilization; genetic regulatory; stabilization genetic ... See more keywords
Virtual Parts Repository 2: Model-Driven Design of Genetic Regulatory Circuits.
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DOI: 10.1021/acssynbio.1c00157
Abstract: Engineering genetic regulatory circuits is key to the creation of biological applications that are responsive to environmental changes. Computational models can assist in understanding especially large and complex circuits for which manual analysis is infeasible,… read more here.
Keywords: genetic regulatory; regulatory circuits; model driven; model ... See more keywords
Meeting Measurement Precision Requirements for Effective Engineering of Genetic Regulatory Networks.
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DOI: 10.1021/acssynbio.1c00488
Abstract: Reliable, predictable engineering of cellular behavior is one of the key goals of synthetic biology. As the field matures, biological engineers will become increasingly reliant on computer models that allow for the rapid exploration of… read more here.
Keywords: genetic regulatory; measurement precision; precision requirements; engineering ... See more keywords
Evolutionary constraints on the complexity of genetic regulatory networks allow predictions of the total number of genetic interactions
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DOI: 10.1038/s41598-019-39866-z
Abstract: Genetic regulatory networks (GRNs) have been widely studied, yet there is a lack of understanding with regards to the final size and properties of these networks, mainly due to no network currently being complete. In… read more here.
Keywords: network; genetic regulatory; number; regulatory networks ... See more keywords
Sampled-Data Stabilization for Fuzzy Genetic Regulatory Networks with Leakage Delays
Sign Up to like & getrecommendations! Published in 2018 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2016.2606477
Abstract: This paper deals with the sampled-data stabilization problem for Takagi-Sugeno (T-S) fuzzy genetic regulatory networks with leakage delays. A novel Lyapunov-Krasovskii functional (LKF) is established by the non-uniform division of the delay intervals with triplex… read more here.
Keywords: networks leakage; sampled data; genetic regulatory; fuzzy genetic ... See more keywords
M-Matrix-Based State Observer Design for Genetic Regulatory Networks With Mixed Delays
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Transactions on Circuits and Systems II: Express Briefs"
DOI: 10.1109/tcsii.2017.2751306
Abstract: Understanding genetic regulatory networks (GRNs) and designing a controller requires access to all the states of the system. However, not all the states of GRN can be experimentally measured in practice. Therefore, a state observer… read more here.
Keywords: state; mixed delays; genetic regulatory; state observer ... See more keywords
${H}_{\infty }$ Filtering for Fuzzy Jumping Genetic Regulatory Networks With Round-Robin Protocol: A Hidden-Markov-Model-Based Approach
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DOI: 10.1109/tfuzz.2019.2939965
Abstract: In this article, a method to design the filter for fuzzy jumping genetic regulatory networks is explored. The case when the filters cannot directly utilize the mode information of the plant is taken into account.… read more here.
Keywords: regulatory networks; genetic regulatory; model; fuzzy jumping ... See more keywords
Oscillatory Behaviors in Genetic Regulatory Networks Mediated by MicroRNA With Time Delays and Reaction-Diffusion Terms
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DOI: 10.1109/tnb.2017.2675446
Abstract: In this paper, we investigate the oscillatory expression in Escherichia coli mediated by microRNA with time delays and reaction-diffusion terms. First of all, the integrated effects of delays and diffusions are first introduced into the… read more here.
Keywords: diffusion; genetic regulatory; reaction diffusion; regulatory networks ... See more keywords
Model Approximation for Switched Genetic Regulatory Networks
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DOI: 10.1109/tnnls.2017.2721448
Abstract: The model approximation problem is studied in this paper for switched genetic regulatory networks (GRNs) with time-varying delays. We focus on constructing a reduced-order model to approximate the high-order GRNs considered under the switching signal… read more here.
Keywords: order; approximation; genetic regulatory; model approximation ... See more keywords