Fetal growth interacts with multilocus genetic score reflecting dopamine signaling capacity to predict spontaneous sugar intake in children
Sign Up to like & getrecommendations! Published in 2018 at "Appetite"
DOI: 10.1016/j.appet.2017.10.021
Abstract: BACKGROUND We have shown that intrauterine growth restriction (IUGR) leads to increased preference for palatable foods at different ages in both humans and rodents. In IUGR rodents, altered striatal dopamine signaling associates with a preference… read more here.
Keywords: growth; genetic score; sugar intake; dopamine signaling ... See more keywords
Fetal Genotype and Maternal Glucose Have Independent and Additive Effects on Birth Weight
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DOI: 10.2337/db17-1188
Abstract: Maternal glycemia is a key determinant of birth weight, but recent large-scale genome-wide association studies demonstrated an important contribution of fetal genetics. It is not known whether fetal genotype modifies the impact of maternal glycemia… read more here.
Keywords: maternal glucose; birth weight; fetal genotype; genetic score ... See more keywords
A Pathway-Based Genetic Score for Oxidative Stress: An Indicator of Host Vulnerability to Phthalate-Associated Adverse Neurodevelopment
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DOI: 10.3390/antiox11040659
Abstract: The developing brain is highly sensitive to environmental disturbances, and adverse exposures can act through oxidative stress. Given that oxidative stress susceptibility is determined partly by genetics, multiple studies have employed genetic scores to explore… read more here.
Keywords: stress; phthalate; score oxidative; oxidative stress ... See more keywords