Genetic and structural basis of the human anti-α-galactosyl antibody response
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123212119
Abstract: Significance The immune response to Galα1–3Galβ1–4GlcNAc (α-gal) has been linked to human allergy and inflammation, and to resistance to xenotransplantation and infection. Here we investigate structural and genetic features that shape the antibody response to… read more here.
Keywords: antibody response; basis human; genetic structural; structural basis ... See more keywords
Genetic and Structural Data on the SARS-CoV-2 Omicron BQ.1 Variant Reveal Its Low Potential for Epidemiological Expansion
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.1101/2022.11.11.516052
Abstract: The BQ.1 SARS-CoV-2 variant, also known as Cerberus, is one of the most recent Omicron descendant lineages. Compared to its direct progenitor BA.5, BQ.1 carries out some additional spike mutations in some key antigenic site… read more here.
Keywords: structural data; omicron; genetic structural; data sars ... See more keywords
Comprehensive whole genome sequence analyses yields novel genetic and structural insights for Intellectual Disability
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DOI: 10.1186/s12864-017-3671-0
Abstract: BackgroundIntellectual Disability (ID) is among the most common global disorders, yet etiology is unknown in ~30% of patients despite clinical assessment. Whole genome sequencing (WGS) is able to interrogate the entire genome, providing potential to… read more here.
Keywords: whole genome; disability; structural insights; genetic structural ... See more keywords
Genetic and Structural Diversity of Prokaryotic Ice-Binding Proteins from the Central Arctic Ocean
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DOI: 10.3390/genes14020363
Abstract: Ice-binding proteins (IBPs) are a group of ecologically and biotechnologically relevant enzymes produced by psychrophilic organisms. Although putative IBPs containing the domain of unknown function (DUF) 3494 have been identified in many taxa of polar… read more here.
Keywords: ice; central arctic; genetic structural; binding proteins ... See more keywords
Khosta: A Genetic and Structural Point of View of the Forgotten Virus
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DOI: 10.3390/idr15030031
Abstract: Bats are well-known to be natural reservoirs of various zoonotic coronaviruses, which have caused outbreaks of severe acute respiratory syndrome (SARS) and the COVID-19 pandemic in 2002 and 2019, respectively. In late 2020, two new… read more here.
Keywords: view forgotten; khosta genetic; genetic structural; khosta ... See more keywords