Clinical impact of minimal residual disease and genetic subtypes on the prognosis of childhood acute lymphoblastic leukemia
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DOI: 10.1002/cncr.34606
Abstract: This study analyzed data from two consecutive protocols for children newly diagnosed with acute lymphoblastic leukemia (ALL) to determine the clinical impact of minimal/measurable residual disease (MRD) and recently identified tumor genetic subtypes. read more here.
Keywords: residual disease; genetic subtypes; impact minimal; lymphoblastic leukemia ... See more keywords
Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma
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DOI: 10.1038/s41598-020-80376-0
Abstract: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease whose prognosis is associated with clinical features, cell-of-origin and genetic aberrations. Recent integrative, multi-omic analyses had led to identifying overlapping genetic DLBCL subtypes. We used targeted… read more here.
Keywords: method classify; genetic subtypes; large cell; diffuse large ... See more keywords
Comorbid and inflammatory characteristics of genetic subtypes of clonal hematopoiesis.
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DOI: 10.1182/bloodadvances.2018024729
Abstract: CH may be associated with broader ill health (worse performance status, increased and potentially novel comorbidities). Serum interleukin-6 is elevated in people with CH and genetic subtypes, providing a view of the human systemic inflammatory… read more here.
Keywords: clonal hematopoiesis; comorbid inflammatory; genetic subtypes; characteristics genetic ... See more keywords