Compensatory Genetic and Transcriptional Cytonuclear Coordination in Allopolyploid Lager Yeast (Saccharomyces pastorianus)
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DOI: 10.1093/molbev/msac228
Abstract: Abstract Cytonuclear coordination between biparental-nuclear genomes and uniparental-cytoplasmic organellar genomes in plants is often resolved by genetic and transcriptional cytonuclear responses. Whether this mechanism also acts in allopolyploid members of other kingdoms is not clear.… read more here.
Keywords: genetic transcriptional; yeast saccharomyces; coordination; transcriptional cytonuclear ... See more keywords
An integrative pan-cancer investigation reveals common genetic and transcriptional alterations of AMPK pathway genes as important predictors of clinical outcomes across major cancer types
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DOI: 10.1186/s12885-020-07286-2
Abstract: Background The AMP-activated protein kinase (AMPK) is an evolutionarily conserved regulator of cellular energy homeostasis. As a nexus for transducing metabolic signals, AMPK cooperates with other energy-sensing pathways to modulate cellular responses to metabolic stressors.… read more here.
Keywords: tumor; genetic transcriptional; pathway genes; cancer ... See more keywords