Articles with "genetic vulnerability" as a keyword



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Interactions between MAOA gene polymorphism and maternal parenting in predicting externalizing and internalizing problems and social competence among Chinese children: Testing the genetic vulnerability and differential susceptibility models

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Published in 2017 at "Infant and Child Development"

DOI: 10.1002/icd.2024

Abstract: The present study aimed to test whether monoamine oxidase A (MAOA) gene polymorphism was a marker of the genetic vulnerability model or the differential susceptibility model by investigating the interaction of MAOA gene polymorphism with… read more here.

Keywords: genetic vulnerability; maoa gene; social competence; maternal parenting ... See more keywords
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AKT1 and genetic vulnerability to bipolar disorder

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Published in 2020 at "Psychiatry Research"

DOI: 10.1016/j.psychres.2019.112677

Abstract: AKT1 encodes a serine/threonine kinase that has as one of its best-known substrates glycogen synthase kinase-3 (GSK3), a primary target for lithium. AKT1 has been previously been implicated as a vulnerability gene for bipolar disorder… read more here.

Keywords: akt1 genetic; vulnerability; vulnerability bipolar; bipolar disorder ... See more keywords
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KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements

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Published in 2020 at "Leukemia"

DOI: 10.1038/s41375-020-1001-z

Abstract: Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group from acetyl-CoA to lysine residues of histones and play a central role in transcriptional regulation in diverse biological processes. Dysregulation of HAT activity can lead… read more here.

Keywords: kat7 genetic; driven mll; acute myeloid; genetic vulnerability ... See more keywords
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Genetic Vulnerability to Opioid Addiction.

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Published in 2020 at "Cold Spring Harbor perspectives in medicine"

DOI: 10.1101/cshperspect.a039735

Abstract: Opioid addiction, also referred to as opioid use disorder, continues to be a devastating problem throughout the world. Familial relation and twin studies have revealed opioid addiction, like other addictive diseases, to be profoundly influenced… read more here.

Keywords: addiction; vulnerability opioid; genetics; opioid addiction ... See more keywords