Joint Associations of Actual Age and Genetically Determined Age at Menarche With Risk of Mortality
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.15297
Abstract: Key Points Question What are the joint associations of actual age and genetically determined age at menarche with risk of all-cause mortality? Findings This cohort study found that that both actual age and genetically determined… read more here.
Keywords: determined age; age; actual age; age menarche ... See more keywords
Is umbilical coiling genetically determined?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Perinatology"
DOI: 10.1038/s41372-018-0078-y
Abstract: ObjectiveAbnormal umbilical cord coiling is associated with adverse perinatal outcomes; however, the etiology of the umbilical coiling pattern is poorly understood.Study designRetrospective cohort of all twin deliveries >20 weeks in 2014. Pregnancies were dichotomized by… read more here.
Keywords: coiling genetically; pattern; cord; umbilical coiling ... See more keywords
Genetically determined telomere length and multiple myeloma risk and outcome
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DOI: 10.1038/s41408-021-00462-y
Abstract: Telomeres are involved in processes like cellular growth, chromosomal stability, and proper segregation to daughter cells. Telomere length measured in leukocytes (LTL) has been investigated in different cancer types, including multiple myeloma (MM). However, LTL… read more here.
Keywords: risk; telomere length; determined telomere; multiple myeloma ... See more keywords
A polymorphic variant in telomere maintenance is associated with worrisome features and high-risk stigmata development in IPMNs.
Sign Up to like & getrecommendations! Published in 2022 at "Carcinogenesis"
DOI: 10.1093/carcin/bgac051
Abstract: Intraductal papillary mucinous neoplasms (IPMNs) are non-obligatory precursor lesions of pancreatic ductal adenocarcinoma (PDAC). The identification of molecular biomarkers able to predict the risk of progression of IPMNs toward malignancy is largely lacking and sorely… read more here.
Keywords: increased risk; ipmns; genetically determined; risk ... See more keywords
Role of the electrocardiogram in differentiating genetically determined dilated cardiomyopathy from athlete's heart
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Clinical Investigation"
DOI: 10.1111/eci.13837
Abstract: Physiological cardiac remodelling in highly trained athletes may overlap with dilated cardiomyopathy (DCM). read more here.
Keywords: genetically determined; role electrocardiogram; differentiating genetically; determined dilated ... See more keywords
Causal Inference for Genetically Determined Levels of High-Density Lipoprotein Cholesterol and Risk of Infectious Disease
Sign Up to like & getrecommendations! Published in 2019 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.119.313381
Abstract: Supplemental Digital Content is available in the text. read more here.
Keywords: determined levels; levels high; high density; inference genetically ... See more keywords
Genetically Determined Levels of Circulating Cytokines and Risk of Stroke: Role of Monocyte Chemoattractant Protein-1
Sign Up to like & getrecommendations! Published in 2019 at "Circulation"
DOI: 10.1161/circulationaha.118.035905
Abstract: Background: Cytokines and growth factors have been implicated in the initiation and propagation of vascular disease. Observational studies have shown associations of their circulating levels with stroke. Our objective was to explore whether genetically determined… read more here.
Keywords: monocyte chemoattractant; risk stroke; risk; study ... See more keywords
Are personalities genetically determined? Inferences from subsocial spiders
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-6172-5
Abstract: Recent research has revealed that polymorphic behavioral strategies shape intra-and interspecific interactions and contribute to fitness in many animal species. A better understanding of the proximate mechanisms underlying these behavioral syndromes will enhance our grasp… read more here.
Keywords: determined inferences; research; personalities genetically; subsocial spiders ... See more keywords
Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Medicine"
DOI: 10.1371/journal.pmed.1002937
Abstract: Background The role of urate in cardiovascular diseases (CVDs) has been extensively investigated in observational studies; however, the extent of any causal effect remains unclear, making it difficult to evaluate its clinical relevance. Methods and… read more here.
Keywords: serum urate; study; disease; urate levels ... See more keywords
Resting heart rate and incident atrial fibrillation: A stratified Mendelian randomization in the AFGen consortium
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DOI: 10.1371/journal.pone.0268768
Abstract: Background Both elevated and low resting heart rates are associated with atrial fibrillation (AF), suggesting a U-shaped relationship. However, evidence for a U-shaped causal association between genetically-determined resting heart rate and incident AF is limited.… read more here.
Keywords: determined resting; genetically determined; heart; resting heart ... See more keywords
Interaction Between Dietary Iron Intake and Genetically Determined Iron Overload: Risk of Islet Autoimmunity and Progression to Type 1 Diabetes in the TEDDY Study.
Sign Up to like & getrecommendations! Published in 2023 at "Diabetes care"
DOI: 10.2337/dc22-1359
Abstract: OBJECTIVE To examine whether iron intake and genetically determined iron overload interact in predisposing to the development of childhood islet autoimmunity (IA) and type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS In The Environmental Determinants… read more here.
Keywords: iron; genetically determined; iron intake; risk ... See more keywords