Articles with "genetically downregulated" as a keyword



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Genetically downregulated Interleukin-6 signalling is associated with a lower risk of frailty.

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Published in 2023 at "Age and ageing"

DOI: 10.1093/ageing/afac318

Abstract: BACKGROUND numerous studies point towards a critical role of Interleukin 6 (IL-6) pathway in frailty pathogenesis yet the causal relationship between the two remains elusive. METHODS we selected genetic variants near the IL-6 receptor locus… read more here.

Keywords: genetically downregulated; risk; risk frailty; associated lower ... See more keywords