Enzymatic Recording of Local Hydrogen Peroxide Generation Using Genetically Encodable Enzyme.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01966
Abstract: Reactive oxygen species (ROS) are endogenously generated in live cells and essential for cell signaling. However, excess ROS generation can cause oxidative damage to biomolecules, which are implicated in various human diseases, including aging. Here,… read more here.
Keywords: hydrogen peroxide; using genetically; generation; h2o2 ... See more keywords
A genetically encodable cell-type-specific protein synthesis inhibitor
Sign Up to like & getrecommendations! Published in 2019 at "Nature Methods"
DOI: 10.1038/s41592-019-0468-x
Abstract: Chemical inhibitors have revealed requirements for protein synthesis that drive cellular plasticity. We developed a genetically encodable protein synthesis inhibitor (gePSI) to achieve cell-type-specific temporal control of protein synthesis. Controlled expression of the gePSI in… read more here.
Keywords: synthesis inhibitor; genetically encodable; protein synthesis; cell ... See more keywords