Genetically Encoded In Vivo Ligation-Driven Targeted Drug Delivery System for Oncotheranostics.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202504119
Abstract: Nanotechnology is transforming cancer diagnostics and treatment through targeted drug delivery. However, the clinical use of nanoparticles faces major challenges, including inconsistent chemical synthesis, low effectiveness, low delivery efficiency, and unintended harm to healthy cells.… read more here.
Keywords: system; drug delivery; delivery; targeted drug ... See more keywords
A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202507046
Abstract: Glutarate is a platform chemical with diversified applications. It is also an endogenous metabolite involved in various physiological processes. Deficiency in glutaryl‐CoA dehydrogenase (GcdH) for glutarate catabolism induces the inherited metabolic disorder glutaric aciduria. In… read more here.
Keywords: transport; glutarate; glusor; genetically encoded ... See more keywords
An Oxidative Bioconjugation Strategy Targeted to a Genetically Encoded 5‐Hydroxytryptophan
Sign Up to like & getrecommendations! Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201800111
Abstract: Approaches that enable the chemoselective, covalent modification of proteins in a site‐specific manner have emerged as a powerful technology for a wide range of applications. The electron‐rich unnatural amino acid 5‐hydroxytryptophan was recently genetically encoded… read more here.
Keywords: bioconjugation strategy; oxidative bioconjugation; genetically encoded; strategy targeted ... See more keywords
Super‐Resolution Microscopy and Single‐Protein Tracking in Live Bacteria Using a Genetically Encoded, Photostable Fluoromodule
Sign Up to like & getrecommendations! Published in 2017 at "Current Protocols in Cell Biology"
DOI: 10.1002/cpcb.21
Abstract: Visualization of dynamic protein structures in live cells is crucial for understanding the mechanisms governing biological processes. Fluorescence microscopy is a sensitive tool for this purpose. In order to image proteins in live bacteria using… read more here.
Keywords: protein; encoded photostable; microscopy; genetically encoded ... See more keywords
Applications of genetically encoded photosensitizer miniSOG: from correlative light electron microscopy to immunophotosensitizing.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600120
Abstract: Genetically encoded photosensitizers (PSs), e.g. ROS generating proteins, correspond to a novel class of PSs that are highly desirable for biological and medical applications since they can be used in combination with a variety of… read more here.
Keywords: microscopy; genetically encoded; correlative light; electron microscopy ... See more keywords
Structural diversity in de novo cyclic peptide ligands from genetically encoded library technologies
Sign Up to like & getrecommendations! Published in 2020 at "Peptide Science"
DOI: 10.1002/pep2.24204
Abstract: Cyclic peptides discovered by genetically encoded library technologies have emerged as a class of promising molecules in chemical biology and drug discovery. Here we review the cyclic peptides identified through these techniques reported in the… read more here.
Keywords: library technologies; cyclic peptide; encoded library; genetically encoded ... See more keywords
Genetically encoded libraries and spider venoms as emerging sources for crop protective peptides
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Peptide Science"
DOI: 10.1002/psc.3600
Abstract: Agricultural crops are targeted by various pathogens (fungi, bacteria, and viruses) and pests (herbivorous arthropods). Antimicrobial and insecticidal peptides are increasingly recognized as eco‐friendly tools for crop protection due to their low propensity for resistance… read more here.
Keywords: genetically encoded; protective peptides; crop; encoded libraries ... See more keywords
Imaging of Genetically Encoded FRET-Based Biosensors to Detect GPCR Activity.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1221-7_11
Abstract: A wealth of assays for screening GPCR activity have been developed. Biosensors that employ Förster Resonance Energy transfer (FRET) are specific and enable dynamic measurements. Moreover, FRET biosensors are ideally suited for the analysis of… read more here.
Keywords: gpcr activity; fret based; genetically encoded; biosensors detect ... See more keywords
Genetically Encoded Biosensors for the Quantitative Analysis of Auxin Dynamics in Plant Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1791-5_11
Abstract: Plants, as sessile organisms, possess complex and intertwined signaling networks to react and adapt their behavior toward different internal and external stimuli. Due to this high level of complexity, the implementation of quantitative molecular tools… read more here.
Keywords: genetically encoded; analysis auxin; auxin; biology ... See more keywords
Probing Protein-Protein Interactions with Genetically Encoded Photoactivatable Cross-Linkers.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7240-1_26
Abstract: Fundamental to all living organisms is the ability of proteins to interact with other biological molecules at the right time and location, with the proper affinity, and to do so reversibly. One well-established technique to… read more here.
Keywords: protein; protein interactions; photoactivatable cross; genetically encoded ... See more keywords
Visualization of Intracellular Hydrogen Peroxide with the Genetically Encoded Fluorescent Probe HyPer in NIH-3T3 Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9424-3_15
Abstract: Reactive oxygen species (ROS) are involved in regulating normal physiological cell functions as second messengers as well as nonspecific damage of biomolecules in a pathological process known as oxidative stress. The HyPer family of genetically… read more here.
Keywords: nih 3t3; probe; hydrogen peroxide; genetically encoded ... See more keywords