Genetics and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: What Have We Learned?
Sign Up to like & getrecommendations! Published in 2017 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.0136
Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are part of a spectrum of severe cutaneous reactions affecting skin and mucous membranes.1 Affected patients usually develop a prodrome of fever and malaise, followed by the… read more here.
Keywords: sjs ten; genetics; johnson syndrome; sjs ... See more keywords
Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2019.2850
Abstract: Importance The Consortium on the Genetics of Schizophrenia (COGS) uses quantitative neurophysiological and neurocognitive endophenotypes with demonstrated deficits in schizophrenia as a platform from which to explore the underlying neural circuitry and genetic architecture. Many… read more here.
Keywords: genome wide; genetics schizophrenia; genetics; association ... See more keywords
Genetics of diabetic neuropathy: Systematic review, meta‐analysis and trial sequential analysis
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50892
Abstract: Diabetic neuropathy (DN) is one of the most common complications of diabetes that occurs in more than 67% of individuals with diabetes. Genetic polymorphisms may play an important role in DN development. However, until now,… read more here.
Keywords: review meta; diabetic neuropathy; analysis; systematic review ... See more keywords
Landscape genetics of the tropical willow Salix humboldtiana: influence of climate, salinity, and orography in an altitudinal gradient.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of botany"
DOI: 10.1002/ajb2.1824
Abstract: CONTEXT Gene flow in riparian ecosystems is influenced by landscape features such as orography, climate, and salinity. The 'downstream increase in genetic diversity' (DIGD) hypothesis states that the unidirectionality of the watercourse causes an accumulation… read more here.
Keywords: gene flow; salinity; landscape; climate salinity ... See more keywords
Evolution and conservation genetics of an insular hemiparasitic plant lineage at the limit of survival: the case of Thesium sect. Kunkeliella in the Canary Islands
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Botany"
DOI: 10.1002/ajb2.1830
Abstract: Abstract Premise The diversification of island flora has been widely studied. However, the role of environmental niches in insular radiation processes has been less investigated. We combined population genetic analyses with species distribution modelling to… read more here.
Keywords: thesium; conservation; thesium sect; sect kunkeliella ... See more keywords
In memoriam: Derek F. Roberts (1925–2016)
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Human Biology"
DOI: 10.1002/ajhb.23027
Abstract: Derek Frank Bruce Roberts was born in London, UK on 20 July 1925. He served in the Lincolnshire Regiment of the British Army from 1943 to 1946 during WW II, and after this army service,… read more here.
Keywords: anthropology; research; genetics; derek ... See more keywords
The behavioral genetics of nonhuman primates: Status and prospects.
Sign Up to like & getrecommendations! Published in 2018 at "American journal of physical anthropology"
DOI: 10.1002/ajpa.23384
Abstract: The complexity and diversity of primate behavior have long attracted the attention of ethologists, psychologists, behavioral ecologists, and neuroscientists. Recent studies have advanced our understanding of the nature of genetic influences on differences in behavior… read more here.
Keywords: genetics; primates status; genetics nonhuman; nonhuman primates ... See more keywords
How White nationalists mobilize genetics: From genetic ancestry and human biodiversity to counterscience and metapolitics.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of physical anthropology"
DOI: 10.1002/ajpa.24150
Abstract: OBJECTIVES Our aim in this study was to understand how genetics ideas are appropriated and mobilized online toward the political projects of White nationalism and the alt right. Studying three different online venues, we investigated… read more here.
Keywords: genetics; genetic ancestry; human biodiversity; metapolitics ... See more keywords
Active genetics comes alive
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202100279
Abstract: Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)‐based “active genetic” elements developed in 2015 bypassed the fundamental rules of traditional genetics. Inherited in a super‐Mendelian fashion, such selfish genetic entities offered a variety of potential applications… read more here.
Keywords: comes alive; genetics comes; active genetics; gene ... See more keywords
The understanding of Parkinson's disease through genetics and new therapies.
Sign Up to like & getrecommendations! Published in 2022 at "Brain and behavior"
DOI: 10.1002/brb3.2577
Abstract: INTRODUCTION Parkinson's disease is one of the progressive neurodegenerative diseases from which people suffer for years. The mechanism of this disease is associated with a decrease in the number of dopaminergic neurons in the substantia… read more here.
Keywords: new therapies; parkinson disease; motor; genetics ... See more keywords
Impact of comprehensive family history and genetic analysis in the multidisciplinary pancreatic tumor clinic setting
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5059
Abstract: Genetic testing is recommended for all pancreatic ductal adenocarcinoma (PDAC) patients. Prior research demonstrates that multidisciplinary pancreatic cancer clinics (MDPCs) improve treatment‐ and survival‐related outcomes for PDAC patients. However, limited information exists regarding the utility… read more here.
Keywords: impact comprehensive; pdac patients; comprehensive family; multidisciplinary pancreatic ... See more keywords