Human accelerated genome regions with value in medical genetics and drug discovery.
Sign Up to like & getrecommendations! Published in 2020 at "Drug discovery today"
DOI: 10.1016/j.drudis.2020.03.001
Abstract: Accumulated evolutionary knowledge not only benefits our understanding of the pathogenesis of diseases, but also help in the search for new drug targets. This is further supported by the recent finding that human accelerated regions… read more here.
Keywords: genetics; genetics drug; drug; human accelerated ... See more keywords
Priority index for human genetics and drug discovery.
Sign Up to like & getrecommendations! Published in 2019 at "Nature Genetics"
DOI: 10.1038/s41588-019-0460-5
Abstract: Although human genetics can help identify new drug targets, the best way to prioritize genes as therapeutic targets is uncertain. A new study describes a framework to prioritize potential targets by integrating genome-wide association data… read more here.
Keywords: index human; genetics drug; genetics; human genetics ... See more keywords