Genetics and Epigenetics: A Historical Overview
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Epigenetics"
DOI: 10.1007/978-981-13-8958-0_1
Abstract: Epigenetics has a fascinating and convoluted history steeped within the fields of embryology and genetics. Here, we introduce genetics and epigenetics to the non-expert reader and give an account of the pivotal discoveries that have… read more here.
Keywords: epigenetics historical; genetics; genetics epigenetics; historical overview ... See more keywords
Genetics and epigenetics in the pathogenesis of primary biliary cholangitis
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Journal of Gastroenterology"
DOI: 10.1007/s12328-017-0799-z
Abstract: Primary biliary cholangitis (PBC) is a chronic, slowly progressive cholestatic autoimmune liver disease predominantly afflicting women. PBC is characterized by the presence of disease-specific antimitochondrial antibodies and the histological destruction of intrahepatic bile ducts, which… read more here.
Keywords: genetics epigenetics; primary biliary; pbc; genetics ... See more keywords
A Convergence of Genetics and Epigenetics in Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.01.035
Abstract: What is at the forefront of the intersection of genetics and epigenetics in cancer and how do we use what we've learned to devise new cures? These are the questions Cell editor Jiaying Tan posed… read more here.
Keywords: convergence genetics; genetics; genetics epigenetics; epigenetics cancer ... See more keywords
Non-alcoholic fatty liver disease establishment and progression: genetics and epigenetics as relevant modulators of the pathology
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2022.2148835
Abstract: Abstract Background Non-alcoholic fatty liver disease (NAFLD) results from metabolic dysfunctions that affect more than one-third of the world population. Over the last decades, scientific investigations have clarified many details on the pathology establishment and… read more here.
Keywords: genetics epigenetics; fatty liver; pathology; establishment progression ... See more keywords
From genetics and epigenetics to the future of precision treatment for obesity
Sign Up to like & getrecommendations! Published in 2017 at "Gastroenterology Report"
DOI: 10.1093/gastro/gox033
Abstract: Abstract Obesity has become a major global health problem, epitomized by excess accumulation of body fat resulting from an imbalance between energy intake and expenditure. The treatments for obesity range from modified nutrition and additional… read more here.
Keywords: genetics epigenetics; epigenetics future; genetics; treatment ... See more keywords
The genetics and epigenetics of satellite centromeres.
Sign Up to like & getrecommendations! Published in 2022 at "Genome research"
DOI: 10.1101/gr.275351.121
Abstract: Centromeres, the chromosomal loci where spindle fibers attach during cell division to segregate chromosomes, are typically found within satellite arrays in plants and animals. Satellite arrays have been difficult to analyze because they comprise megabases… read more here.
Keywords: genetics epigenetics; satellite arrays; epigenetics satellite; satellite centromeres ... See more keywords
Genetics, epigenetics, and transcriptomics of preterm birth
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13600
Abstract: Preterm birth contributes significantly to neonatal mortality and morbidity. Despite its global significance, there has only been limited progress in preventing preterm birth. Spontaneous preterm birth (sPTB) results from a wide variety of pathological processes.… read more here.
Keywords: genetics epigenetics; preterm birth; transcriptomics preterm; birth ... See more keywords
From genetics to epigenetics: new insights into keloid scarring
Sign Up to like & getrecommendations! Published in 2017 at "Cell Proliferation"
DOI: 10.1111/cpr.12326
Abstract: Keloid scarring is a dermal fibroproliferative response characterized by excessive and progressive deposition of collagen; aetiology and molecular pathology underlying keloid formation and progression remain unclear. Genetic predisposition is important in the pathogenic processes of… read more here.
Keywords: genetics epigenetics; keloid formation; genetics; epigenetics new ... See more keywords
Genetics and epigenetics of autism: A Review
Sign Up to like & getrecommendations! Published in 2018 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.12606
Abstract: Autism is a developmental disorder that starts before age 3 years, and children with autism have impairment in both social interaction and communication, and have restricted, repetitive, and stereotyped patterns of behavior, interests, and activities. There… read more here.
Keywords: genetics epigenetics; autism review; autism; genetics ... See more keywords
A Perspective of the Cross-Tissue Interplay of Genetics, Epigenetics, and Transcriptomics, and Their Relation to Brain Based Phenotypes in Schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00343
Abstract: Genetic association studies of psychiatric disorders have provided unprecedented insight into disease risk profiles with high confidence. Yet, the next research challenge is how to translate this rich information into mechanisms of disease, and further… read more here.
Keywords: epigenetics transcriptomics; genetics epigenetics; cross tissue; genetics ... See more keywords
Mitochondrial Genetics and Epigenetics in Osteoarthritis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.01335
Abstract: During recent years, the significant influence of mitochondria on osteoarthritis (OA), the most common joint disease, has been consistently demonstrated. Not only mitochondrial dysfunction but also mitochondrial genetic polymorphisms, specifically the mitochondrial DNA haplogroups, have… read more here.
Keywords: genetics epigenetics; mitochondrial genetics; genetics; influence ... See more keywords