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Geniposide inhibits glucolipotoxicity and cooperates with Txnip knockdown to potentiate cell adaption to endoplasmic reticulum stress in pancreatic beta cells

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0 Published in 2020 at "Cell Biology International"

DOI: 10.1002/cbin.11350

Abstract: Thioredoxin‐interacting protein (Txnip), a negative regulator of thioredoxin, has become an attractive therapeutic target to alleviate metabolic diseases. Our previous data demonstrated that geniposide improved glucose‐stimulated insulin secretion by accelerating Txnip degradation and prevented the… read more here.

Keywords: inhibits glucolipotoxicity; geniposide inhibits; pancreatic cells; cell ... See more keywords