Protein-to-genome alignment with miniprot
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btad014
Abstract: Abstract Motivation Protein-to-genome alignment is critical to annotating genes in non-model organisms. While there are a few tools for this purpose, all of them were developed over 10 years ago and did not incorporate the… read more here.
Keywords: protein genome; alignment miniprot; genome alignment;
A genome alignment of 120 mammals highlights ultraconserved element variability and placenta-associated enhancers
Sign Up to like & getrecommendations! Published in 2020 at "GigaScience"
DOI: 10.1093/gigascience/giz159
Abstract: Abstract Background Multiple alignments of mammalian genomes have been the basis of many comparative genomic studies aiming at annotating genes, detecting regions under evolutionary constraint, and studying genome evolution. A key factor that affects the… read more here.
Keywords: alignment 120; alignment; mammals highlights; placenta ... See more keywords
seq-seq-pan: building a computational pan-genome data structure on whole genome alignment
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-4401-3
Abstract: BackgroundThe increasing application of next generation sequencing technologies has led to the availability of thousands of reference genomes, often providing multiple genomes for the same or closely related species. The current approach to represent a… read more here.
Keywords: seq seq; whole genome; pan; genome alignment ... See more keywords
Comparative analysis of alignment-free genome clustering and whole genome alignment-based phylogenomic relationship of coronaviruses
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DOI: 10.1371/journal.pone.0264640
Abstract: The SARS-CoV-2 is the third coronavirus in addition to SARS-CoV and MERS-CoV that causes severe respiratory syndrome in humans. All of them likely crossed the interspecific barrier between animals and humans and are of zoonotic… read more here.
Keywords: alignment free; genome alignment; alignment; genome ... See more keywords