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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7343-9_17
Abstract: Phages are complex biomolecular machineries that have to survive in a bacterial world. Phage genomes show many adaptations to their lifestyle such as shorter genes, reduced capacity for redundant DNA sequences, and the inclusion of…
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Keywords:
pipeline;
phage genome;
phage;
annotation ... See more keywords
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Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9173-0_8
Abstract: Comparing multiple related genomes can help to improve their structural annotation. The accuracy and consistency of the predicted exon-intron structures of the protein coding genes can be higher when considering all genomes at once rather…
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Keywords:
augustus;
multi genome;
annotation;
annotation augustus ... See more keywords
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Published in 2025 at "Scientific Data"
DOI: 10.1038/s41597-025-04962-5
Abstract: Rhodiola kirilowii, a perennial medical herb native to China, is highly valued for its detoxification and anti-swelling properties, as well as its role as an adaptogen, making it an intriguing subject for understanding its medicinal…
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Keywords:
level genome;
rhodiola kirilowii;
genome annotation;
chromosome level ... See more keywords
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Published in 2024 at "Journal of Computational Biology"
DOI: 10.1089/cmb.2024.0667
Abstract: An annotation is a set of genomic intervals sharing a particular function or property. Examples include genes or their exons, sequence repeats, regions with a particular epigenetic state, and copy number variants. A common task…
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Keywords:
aware analysis;
context aware;
genome annotation;
annotation ... See more keywords
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Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbab004
Abstract: Humans have coexisted with pathogenic microorganisms throughout its history of evolution. We have never halted the exploration of pathogenic microorganisms. With the improvement of genome-sequencing technology and the continuous reduction of sequencing costs, an increasing…
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Keywords:
disease causing;
causing microorganisms;
annotation disease;
annotation ... See more keywords
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Published in 2021 at "Nucleic acids research"
DOI: 10.1093/nar/gkaa1105
Abstract: The Reference Sequence (RefSeq) project at the National Center for Biotechnology Information (NCBI) contains nearly 200 000 bacterial and archaeal genomes and 150 million proteins with up-to-date annotation. Changes in the Prokaryotic Genome Annotation Pipeline…
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Keywords:
refseq;
protein family;
annotation;
prokaryotic genome ... See more keywords
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Published in 2025 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaf335
Abstract: Abstract The Bakta command line application is widely used and one of the most established tools for bacterial genome annotation. It balances comprehensive annotation with computational efficiency via alignment-free sequence identifications. However, the usage of…
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Keywords:
command line;
genome annotation;
bakta web;
web rapid ... See more keywords
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Published in 2020 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000341
Abstract: Although gene-finding in bacterial genomes is relatively straightforward, the automated assignment of gene function is still challenging, resulting in a vast quantity of hypothetical sequences of unknown function. But how prevalent are hypothetical sequences across…
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Keywords:
completeness;
annotation coverage;
annotation;
annotation completeness ... See more keywords
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Published in 2018 at "Genome research"
DOI: 10.1101/gr.233460.117
Abstract: The recent introductions of low-cost, long-read, and read-cloud sequencing technologies coupled with intense efforts to develop efficient algorithms have made affordable, high-quality de novo sequence assembly a realistic proposition. The result is an explosion of…
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Keywords:
comparative annotation;
annotation;
annotation toolkit;
genome annotation ... See more keywords
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Published in 2024 at "Genome Research"
DOI: 10.1101/gr.279864.124
Abstract: While the production of a draft genome has become more accessible due to long-read sequencing, the annotation of these new genomes has not been developed at the same pace. Long-read RNA sequencing offers a promising…
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Keywords:
read rna;
long read;
genome annotation;
annotation ... See more keywords
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Published in 2018 at "Plant Physiology"
DOI: 10.1104/pp.18.00848
Abstract: The long Read Annotation (LoReAn) pipeline provides automated genome annotation with superior performance by incorporating single-molecule cDNA sequencing data. Single-molecule full-length complementary DNA (cDNA) sequencing can aid genome annotation by revealing transcript structure and alternative…
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Keywords:
long read;
annotation;
read annotation;
cdna ... See more keywords