Articles with "genome annotation" as a keyword



Phage Genome Annotation Using the RAST Pipeline.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7343-9_17

Abstract: Phages are complex biomolecular machineries that have to survive in a bacterial world. Phage genomes show many adaptations to their lifestyle such as shorter genes, reduced capacity for redundant DNA sequences, and the inclusion of… read more here.

Keywords: pipeline; phage genome; phage; annotation ... See more keywords
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Multi-Genome Annotation with AUGUSTUS.

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Published in 2019 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9173-0_8

Abstract: Comparing multiple related genomes can help to improve their structural annotation. The accuracy and consistency of the predicted exon-intron structures of the protein coding genes can be higher when considering all genomes at once rather… read more here.

Keywords: augustus; multi genome; annotation; annotation augustus ... See more keywords

Chromosome-level genome and annotation of the tetraploid Rhodiola kirilowii

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Published in 2025 at "Scientific Data"

DOI: 10.1038/s41597-025-04962-5

Abstract: Rhodiola kirilowii, a perennial medical herb native to China, is highly valued for its detoxification and anti-swelling properties, as well as its role as an adaptogen, making it an intriguing subject for understanding its medicinal… read more here.

Keywords: level genome; rhodiola kirilowii; genome annotation; chromosome level ... See more keywords

Fast Context-Aware Analysis of Genome Annotation Colocalization

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Published in 2024 at "Journal of Computational Biology"

DOI: 10.1089/cmb.2024.0667

Abstract: An annotation is a set of genomic intervals sharing a particular function or property. Examples include genes or their exons, sequence repeats, regions with a particular epigenetic state, and copy number variants. A common task… read more here.

Keywords: aware analysis; context aware; genome annotation; annotation ... See more keywords

Genome annotation of disease-causing microorganisms

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Published in 2021 at "Briefings in bioinformatics"

DOI: 10.1093/bib/bbab004

Abstract: Humans have coexisted with pathogenic microorganisms throughout its history of evolution. We have never halted the exploration of pathogenic microorganisms. With the improvement of genome-sequencing technology and the continuous reduction of sequencing costs, an increasing… read more here.

Keywords: disease causing; causing microorganisms; annotation disease; annotation ... See more keywords

RefSeq: expanding the Prokaryotic Genome Annotation Pipeline reach with protein family model curation

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Published in 2021 at "Nucleic acids research"

DOI: 10.1093/nar/gkaa1105

Abstract: The Reference Sequence (RefSeq) project at the National Center for Biotechnology Information (NCBI) contains nearly 200 000 bacterial and archaeal genomes and 150 million proteins with up-to-date annotation. Changes in the Prokaryotic Genome Annotation Pipeline… read more here.

Keywords: refseq; protein family; annotation; prokaryotic genome ... See more keywords

Bakta Web – rapid and standardized genome annotation on scalable infrastructures

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Published in 2025 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaf335

Abstract: Abstract The Bakta command line application is widely used and one of the most established tools for bacterial genome annotation. It balances comprehensive annotation with computational efficiency via alignment-free sequence identifications. However, the usage of… read more here.

Keywords: command line; genome annotation; bakta web; web rapid ... See more keywords
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An assessment of genome annotation coverage across the bacterial tree of life

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Published in 2020 at "Microbial Genomics"

DOI: 10.1099/mgen.0.000341

Abstract: Although gene-finding in bacterial genomes is relatively straightforward, the automated assignment of gene function is still challenging, resulting in a vast quantity of hypothetical sequences of unknown function. But how prevalent are hypothetical sequences across… read more here.

Keywords: completeness; annotation coverage; annotation; annotation completeness ... See more keywords

Comparative Annotation Toolkit (CAT) - Simultaneous Clade and Personal Genome Annotation

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Published in 2018 at "Genome research"

DOI: 10.1101/gr.233460.117

Abstract: The recent introductions of low-cost, long-read, and read-cloud sequencing technologies coupled with intense efforts to develop efficient algorithms have made affordable, high-quality de novo sequence assembly a realistic proposition. The result is an explosion of… read more here.

Keywords: comparative annotation; annotation; annotation toolkit; genome annotation ... See more keywords

Evaluation of strategies for evidence-driven genome annotation using long-read RNA-seq

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Published in 2024 at "Genome Research"

DOI: 10.1101/gr.279864.124

Abstract: While the production of a draft genome has become more accessible due to long-read sequencing, the annotation of these new genomes has not been developed at the same pace. Long-read RNA sequencing offers a promising… read more here.

Keywords: read rna; long read; genome annotation; annotation ... See more keywords

Long-Read Annotation: Automated Eukaryotic Genome Annotation Based on Long-Read cDNA Sequencing1[OPEN]

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Published in 2018 at "Plant Physiology"

DOI: 10.1104/pp.18.00848

Abstract: The long Read Annotation (LoReAn) pipeline provides automated genome annotation with superior performance by incorporating single-molecule cDNA sequencing data. Single-molecule full-length complementary DNA (cDNA) sequencing can aid genome annotation by revealing transcript structure and alternative… read more here.

Keywords: long read; annotation; read annotation; cdna ... See more keywords