Performance comparisons of methylation and structural variants from low-input whole-genome methylation sequencing
Sign Up to like & getrecommendations! Published in 2023 at "Epigenomics"
DOI: 10.2217/epi-2022-0453
Abstract: Aim Whole-genome methylation sequencing carries both DNA methylation and structural variant information (single nucleotide variant [SNV]; copy number variant [CNV]); however, limited data is available on the reliability of obtaining this information simultaneously from low-input… read more here.
Keywords: methylation; methylation sequencing; genome methylation; low input ... See more keywords
High levels of global genome methylation in patients with retinoblastoma
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DOI: 10.3892/ol.2020.11613
Abstract: Retinoblastoma is a tumor of the embryonic neural retina in young children. The DNA methyltransferase 1 (DNMT1) gene has been demonstrated to be transcriptionally activated in cells lacking retinoblastoma 1 (RB1). Thus, there is a… read more here.
Keywords: methylation; levels global; genome methylation; patients retinoblastoma ... See more keywords