Articles with "genome modulation" as a keyword



Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells

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Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202502593

Abstract: Cas12j‐8 is a compact Cas nuclease discovered from the metagenome of giant bacteriophages, consisting of only 717 amino acids and recognizing the ‘5‐TTN‐3′ protospacer adjacent motif (PAM) sequence. However, its low gene editing efficiency in… read more here.

Keywords: genome modulation; cas12j versatile; engineered cas12j; versatile platform ... See more keywords