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Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-01716-y
Abstract: Simple sequence repeats (SSRs) are rare (approximately 1%) in most genomes and are generally considered to have no function. However, penaeid shrimp genomes have a high proportion of SSRs (>23%), raising the question of whether…
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Keywords:
genome plasticity;
adaptive evolution;
penaeid shrimp;
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Published in 2022 at "Medical Mycology"
DOI: 10.1093/mmy/myac072.p335
Abstract: Abstract Poster session 3, September 23, 2022, 12:30 PM - 1:30 PM Objectives Candida albicans is the most implicated fungal species that grows as a commensal or opportunistic pathogen in the human host. The genome…
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Keywords:
adaptation;
candida albicans;
survival;
host ... See more keywords
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Published in 2018 at "Infection and Immunity"
DOI: 10.1128/iai.00331-18
Abstract: Therapy for bacteremia caused by Staphylococcus aureus is often ineffective, even when treatment conditions are optimal according to experimental protocols. Adapted subclones, such as those bearing mutations that attenuate agr-mediated virulence activation, are associated with…
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Keywords:
staphylococcus aureus;
virulence;
genome plasticity;
infection ... See more keywords
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Published in 2018 at "BMC Genomics"
DOI: 10.1186/s12864-018-4680-3
Abstract: BackgroundPyrenophora tritici-repentis (Ptr) is a necrotrophic fungal pathogen that causes the major wheat disease, tan spot. We set out to provide essential genomics-based resources in order to better understand the pathogenicity mechanisms of this important…
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Keywords:
fungal pathogen;
pathogen;
tritici repentis;
genome plasticity ... See more keywords
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Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1058741
Abstract: Heterochromatin is a repressive chromatin state that plays key roles in the functional organisation of eukaryotic genomes. In fungal plant pathogens, effector genes that are required for host colonization tend to be associated with heterochromatic…
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Keywords:
heterochromatin;
transposable elements;
zymoseptoria tritici;
fungal plant ... See more keywords
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Published in 2022 at "Genes"
DOI: 10.3390/genes13111999
Abstract: Non-random spatial organization of the chromosomal material inside the nuclei of brain cells emerges as an important regulatory layer of genome organization and function in health and disease. Here, we discuss how integrative approaches assessing…
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Keywords:
normal diseased;
plasticity normal;
diseased neurodevelopment;
organization ... See more keywords