Real‐world assessment of comprehensive genome profiling impact on clinical outcomes: A single‐institution study in Japan
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Medicine"
DOI: 10.1002/cam4.70249
Abstract: Comprehensive genome profiling (CGP) has revolutionized healthcare by offering personalized medicine opportunities. However, its real‐world utility and impact remain incompletely understood. This study examined the extent to which CGP leads to genomically matched therapy and… read more here.
Keywords: comprehensive genome; real world; genome profiling; medicine ... See more keywords
A novel comprehensive cancer genome profiling for non‐metastatic prostate cancer: study protocol with FPG500 to detect actionable alterations representative of progressive disease
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DOI: 10.1111/bju.70019
Abstract: Prostate cancer (PCa) presents with substantial biological heterogeneity and variable clinical outcomes. While genomic alterations in high‐risk and locally advanced cases may signal early progression or micrometastatic disease, their clinical finding and utility remains underexplored.… read more here.
Keywords: cancer; disease; prostate cancer; comprehensive cancer ... See more keywords
Abstract 3638: Analysis of the clinical benefit of comprehensive genome profiling derived therapeutic associations in advanced cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-3638
Abstract: Modern cancer care has seen an increase in the use of targeted therapies and the number of FDA-approved biomarkers. To take advantage of these options, many have turned to commercially available comprehensive genome profiling (CGP)… read more here.
Keywords: therapy; analysis; comprehensive genome; genome profiling ... See more keywords
Abstract 262: Heat Map Analysis, a new integrated pathway scoring system for cancer genome profiling
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-262
Abstract: Background: Cancer genome profiling using next-generation sequencing (NGS) has become widespread. Multiple genetic abnormalities including variant of unknown significance (VUS) have been detected in various cancer types. However, there is a lack of an integrated… read more here.
Keywords: heat map; map analysis; analysis; genome profiling ... See more keywords
The genome profiling method can be applied for species identification of biological materials collected at crime scenes
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DOI: 10.1186/s12863-019-0753-9
Abstract: BackgroundVarious biological materials unrelated to humans are found at crime scenes and it is often important to elucidate the origin of these materials. A genetic locus common to several species is conventionally PCR-amplified with universal… read more here.
Keywords: profiling method; crime scenes; method; genome profiling ... See more keywords