Genome Regulation by Polycomb and Trithorax: 70 Years and Counting
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.08.002
Abstract: Polycomb (PcG) and Trithorax (TrxG) group proteins are evolutionarily conserved chromatin-modifying factors originally identified as part of an epigenetic cellular memory system that maintains repressed or active gene expression states. Recently, they have been shown… read more here.
Keywords: polycomb; polycomb trithorax; regulation polycomb; trithorax years ... See more keywords
Know when to fold ‘em: Polycomb complexes in oncogenic 3D genome regulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.986319
Abstract: Chromatin is spatially and temporally regulated through a series of orchestrated processes resulting in the formation of 3D chromatin structures such as topologically associating domains (TADs), loops and Polycomb Bodies. These structures are closely linked… read more here.
Keywords: know fold; pcg complexes; genome regulation; fold polycomb ... See more keywords