Fowlpox virus: an overview of its classification, morphology and genome, replication mechanisms, uses as vaccine vector and disease dynamics
Sign Up to like & getrecommendations! Published in 2021 at "World's Poultry Science Journal"
DOI: 10.1080/00439339.2021.1959278
Abstract: Fowlpox virus (FWPV) is a complex cytoplasmic DNA virus belonging to the Family- Poxviridae, Subfamily-Chordopoxvirinae and Genus-Avipoxviruses. The large size of the genome accommodates multiple g... read more here.
Keywords: virus overview; overview classification; genome replication; fowlpox virus ... See more keywords
Repriming DNA synthesis: an intrinsic restart pathway that maintains efficient genome replication
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab176
Abstract: Abstract To bypass a diverse range of fork stalling impediments encountered during genome replication, cells possess a variety of DNA damage tolerance (DDT) mechanisms including translesion synthesis, template switching, and fork reversal. These pathways function… read more here.
Keywords: dna synthesis; restart pathway; genome replication; efficient genome ... See more keywords
Calcium Influx Regulates the Replication of Several Negative-Strand RNA Viruses Including Severe Fever with Thrombocytopenia Syndrome Virus
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.00015-23
Abstract: SFTS is an emerging infectious disease and has a high mortality rate of up to 30%. There are no licensed vaccines or antivirals against SFTS. ABSTRACT Negative-strand RNA viruses (NSVs) represent one of the most… read more here.
Keywords: calcium; genome replication; replication; calcium channel ... See more keywords
Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides
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DOI: 10.1371/journal.ppat.1007036
Abstract: At the culmination of poliovirus (PV) multiplication, membranes are observed that contain phosphatidylinositol-4-phosphate (PI4P) and appear as vesicular clusters in cross section. Induction and remodeling of PI4P and membranes prior to or concurrent with genome… read more here.
Keywords: vesicular clusters; genome replication; membranous structures; spatiotemporal dynamics ... See more keywords
Herpes simplex virus co-infection facilitates rolling circle replication of the adeno-associated virus genome
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1009638
Abstract: Adeno-associated virus (AAV) genome replication only occurs in the presence of a co-infecting helper virus such as adenovirus type 5 (AdV5) or herpes simplex virus type 1 (HSV-1). AdV5-supported replication of the AAV genome has… read more here.
Keywords: genome replication; aav genome; associated virus; adeno associated ... See more keywords
The mechanism of genome replication and transcription in bunyaviruses
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1011060
Abstract: Bunyaviruses are negative sense, single-strand RNA viruses that infect a wide range of vertebrate, invertebrate and plant hosts. WHO lists three bunyavirus diseases as priority diseases requiring urgent development of medical countermeasures highlighting their high… read more here.
Keywords: genome replication; replication; replication transcription; mechanism genome ... See more keywords
Ribosome Pausing at Inefficient Codons at the End of the Replicase Coding Region Is Important for Hepatitis C Virus Genome Replication
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21186955
Abstract: Hepatitis C virus (HCV) infects liver cells and often causes chronic infection, also leading to liver cirrhosis and cancer. In the cytoplasm, the viral structural and non-structural (NS) proteins are directly translated from the plus… read more here.
Keywords: inefficient codons; genome replication; replicase; hepatitis virus ... See more keywords
Exogenous Rubella Virus Capsid Proteins Enhance Virus Genome Replication
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11060683
Abstract: Enhanced replication of rubella virus (RuV) and replicons by de novo synthesized viral structural proteins has been previously described. Such enhancement can occur by viral capsid proteins (CP) alone in trans. It is not clear… read more here.
Keywords: capsid proteins; genome replication; replication; rna ... See more keywords
Effects of Caffeine, a DNA Damage Response Inhibitor, on Papillomavirus Genome Replication
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11111298
Abstract: Epidemiological studies have revealed that caffeinated coffee imparts a reduced risk of oropharyngeal cancer, of which human papillomavirus (HPV) is one of the causative agents. Caffeine is a known inhibitor of the DNA damage response… read more here.
Keywords: effects caffeine; papillomavirus; dna damage; genome replication ... See more keywords
Vemurafenib Inhibits Enterovirus A71 Genome Replication and Virus Assembly
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15091067
Abstract: Enterovirus A71 (EV-A71) infection is a major cause of hand, foot, and mouth disease (HFMD), which may be occasionally associated with severe neurological complications. There is currently a lack of treatment options for EV-A71 infection.… read more here.
Keywords: genome replication; replication; a71 genome; anti a71 ... See more keywords
An evolutionary model identifies the main evolutionary biases for the evolution of genome-replication profiles
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DOI: 10.7554/elife.63542
Abstract: Recent results comparing the temporal program of genome replication of yeast species belonging to the Lachancea clade support the scenario that the evolution of the replication timing program could be mainly driven by correlated acquisition… read more here.
Keywords: evolutionary biases; replication; replication timing; genome replication ... See more keywords