Bleomycin-induced genome structural variations in normal, non-tumor cells
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DOI: 10.1038/s41598-018-34580-8
Abstract: Many anticancer drugs are genotoxic agents inducing DNA breaks in actively proliferating cancer cells. However, these same drugs also induce mutations, mostly genome structural variations (GSVs). The detection of GSVs in normal cells and tissues… read more here.
Keywords: bleomycin induced; structural variations; normal cells; normal non ... See more keywords
Extensive homoeologous genome exchanges in allopolyploid crops revealed by mRNAseqâbased visualization
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DOI: 10.1111/pbi.12657
Abstract: Summary Polyploidy, the possession of multiple sets of chromosomes, has been a predominant factor in the evolution and success of the angiosperms. Although artificially formed allopolyploids show a high rate of genome rearrangement, the genomes… read more here.
Keywords: variation; extensive homoeologous; visualization; genome structural ... See more keywords