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   Articles with "genome structure" as a keyword



Genome structure and genetic diversity in the Ebola virus.

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recommendations! Published in 2021 at "Current opinion in pharmacology"

DOI: 10.1016/j.coph.2021.06.010

Abstract: Ebola is a deadly pathogen responsible for Ebola virus disease, first came to prominence in the year 1976. This rapidly evolving virus imposed a serious threat to the human population in the last few decades… read more here.

Keywords: structure genetic; ebola virus; genome structure; structure ... See more keywords

A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells.

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recommendations! Published in 2021 at "British journal of cancer"

DOI: 10.1038/s41416-021-01579-4

Abstract: BACKGROUND KLF5 plays a crucial role in stem cells of colorectum in cooperation with Lgr5 gene. In this study, we aimed to explicate a regulatory mechanism of the KLF5 gene product from a view of… read more here.

Keywords: three dimensional; dimensional genome; genome structure; klf5 ... See more keywords

Evolutionary divergent kinetoplast genome structure and RNA editing patterns in the trypanosomatid Vickermania

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recommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2426887122

Abstract: Significance The study of trypanosomatid flagellates has continually broadened our knowledge of eukaryotic biology and highlighted the limits of our assumptions based on model organisms. The impacts of gains and losses of DNA units, such… read more here.

Keywords: structure rna; genome structure; evolutionary divergent; rna ... See more keywords

IAGS: Inferring Ancestor Genome Structure under a Wide Range of Evolutionary Scenarios

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recommendations! Published in 2022 at "Molecular Biology and Evolution"

DOI: 10.1093/molbev/msac041

Abstract: Abstract Significant improvements in genome sequencing and assembly technology have led to increasing numbers of high-quality genomes, revealing complex evolutionary scenarios such as multiple whole-genome duplication events, which hinders ancestral genome reconstruction via the currently… read more here.

Keywords: ancestor genome; evolutionary scenarios; inferring ancestor; genome ... See more keywords

Three-dimensional genome structure of a single cell

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recommendations! Published in 2019 at "Science"

DOI: 10.1126/science.aaz7774

Abstract: Chromosome organization in diploid cells reveals a structural basis for smell Since the 1880s, scientists such as Carl Rabl have been looking at cell nuclei under a microscope and speculating about their three-dimensional (3D) structure.… read more here.

Keywords: three dimensional; dimensional genome; genome structure; structure ... See more keywords

ARGV: 3D genome structure exploration using augmented reality

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recommendations! Published in 2024 at "BMC Bioinformatics"

DOI: 10.1186/s12859-024-05882-8

Abstract: Over the past two decades, scientists have increasingly realized the importance of the three-dimensional (3D) genome organization in regulating cellular activity. Hi-C and related experiments yield 2D contact matrices that can be used to infer… read more here.

Keywords: genome structure; argv genome; structure; structure exploration ... See more keywords

Comparative genomics of Eucalyptus and Corymbia reveals low rates of genome structural rearrangement

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recommendations! Published in 2017 at "BMC Genomics"

DOI: 10.1186/s12864-017-3782-7

Abstract: BackgroundPrevious studies suggest genome structure is largely conserved between Eucalyptus species. However, it is unknown if this conservation extends to more divergent eucalypt taxa. We performed comparative genomics between the eucalypt genera Eucalyptus and Corymbia.… read more here.

Keywords: comparative genomics; genome structure; structure; genomics eucalyptus ... See more keywords
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Complete chloroplast genomes of eight Delphinium taxa (Ranunculaceae) endemic to Xinjiang, China: insights into genome structure, comparative analysis, and phylogenetic relationships

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recommendations! Published in 2024 at "BMC Plant Biology"

DOI: 10.1186/s12870-024-05279-y

Abstract: Delphinium L. represents a taxonomically intricate genus of significant phylogenetic and economic importance in Ranunculaceae. Despite the existence of few chloroplast genome datasets, a comprehensive understanding of genome structures and selective pressures within the genus… read more here.

Keywords: chloroplast genomes; genome structure; delphinium taxa; delphinium ... See more keywords

Large Fragment InDels Reshape Genome Structure of Porcine Alveolar Macrophage 3D4/21 Cells

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recommendations! Published in 2022 at "Genes"

DOI: 10.3390/genes13091515

Abstract: The porcine monomyeloid cell line, or 3D4/21 cells, is an effective tool to study the immune characteristics and virus infection mechanism of pigs. Due to the introduction of the neomycin resistance gene and the SV40… read more here.

Keywords: fragment indels; large fragment; structure; 3d4 cells ... See more keywords

HPV16 and HPV18 Genome Structure, Expression, and Post-Transcriptional Regulation

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23094943

Abstract: Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high-risk HPVs, are responsible for ~70% of all HPV-related cervical… read more here.

Keywords: rna; hpv16 hpv18; genome structure; hpv18 genome ... See more keywords

Impact of LTR-Retrotransposons on Genome Structure, Evolution, and Function in Curcurbitaceae Species

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231710158

Abstract: Long terminal repeat (LTR)-retrotransposons (LTR-RTs) comprise a major portion of many plant genomes and may exert a profound impact on genome structure, function, and evolution. Although many studies have focused on these elements in an… read more here.

Keywords: function; ltr retrotransposons; ltr rts; genome structure ... See more keywords