Genome structure and genetic diversity in the Ebola virus.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2021.06.010
Abstract: Ebola is a deadly pathogen responsible for Ebola virus disease, first came to prominence in the year 1976. This rapidly evolving virus imposed a serious threat to the human population in the last few decades… read more here.
Keywords: structure genetic; ebola virus; genome structure; structure ... See more keywords
A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of cancer"
DOI: 10.1038/s41416-021-01579-4
Abstract: BACKGROUND KLF5 plays a crucial role in stem cells of colorectum in cooperation with Lgr5 gene. In this study, we aimed to explicate a regulatory mechanism of the KLF5 gene product from a view of… read more here.
Keywords: three dimensional; dimensional genome; genome structure; klf5 ... See more keywords
IAGS: Inferring Ancestor Genome Structure under a Wide Range of Evolutionary Scenarios
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac041
Abstract: Abstract Significant improvements in genome sequencing and assembly technology have led to increasing numbers of high-quality genomes, revealing complex evolutionary scenarios such as multiple whole-genome duplication events, which hinders ancestral genome reconstruction via the currently… read more here.
Keywords: ancestor genome; evolutionary scenarios; inferring ancestor; genome ... See more keywords
Three-dimensional genome structure of a single cell
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aaz7774
Abstract: Chromosome organization in diploid cells reveals a structural basis for smell Since the 1880s, scientists such as Carl Rabl have been looking at cell nuclei under a microscope and speculating about their three-dimensional (3D) structure.… read more here.
Keywords: three dimensional; dimensional genome; genome structure; structure ... See more keywords
Comparative genomics of Eucalyptus and Corymbia reveals low rates of genome structural rearrangement
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-3782-7
Abstract: BackgroundPrevious studies suggest genome structure is largely conserved between Eucalyptus species. However, it is unknown if this conservation extends to more divergent eucalypt taxa. We performed comparative genomics between the eucalypt genera Eucalyptus and Corymbia.… read more here.
Keywords: comparative genomics; genome structure; structure; genomics eucalyptus ... See more keywords
Large Fragment InDels Reshape Genome Structure of Porcine Alveolar Macrophage 3D4/21 Cells
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13091515
Abstract: The porcine monomyeloid cell line, or 3D4/21 cells, is an effective tool to study the immune characteristics and virus infection mechanism of pigs. Due to the introduction of the neomycin resistance gene and the SV40… read more here.
Keywords: fragment indels; large fragment; structure; 3d4 cells ... See more keywords
HPV16 and HPV18 Genome Structure, Expression, and Post-Transcriptional Regulation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094943
Abstract: Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high-risk HPVs, are responsible for ~70% of all HPV-related cervical… read more here.
Keywords: rna; hpv16 hpv18; genome structure; hpv18 genome ... See more keywords
Impact of LTR-Retrotransposons on Genome Structure, Evolution, and Function in Curcurbitaceae Species
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231710158
Abstract: Long terminal repeat (LTR)-retrotransposons (LTR-RTs) comprise a major portion of many plant genomes and may exert a profound impact on genome structure, function, and evolution. Although many studies have focused on these elements in an… read more here.
Keywords: function; ltr retrotransposons; ltr rts; genome structure ... See more keywords