Mitochondrial replacement by genome transfer in human oocytes: Efficacy, concerns, and legality
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DOI: 10.1002/rmb2.12356
Abstract: Pathogenic mitochondrial (mt)DNA mutations, which often cause life‐threatening disorders, are maternally inherited via the cytoplasm of oocytes. Mitochondrial replacement therapy (MRT) is expected to prevent second‐generation transmission of mtDNA mutations. However, MRT may affect the… read more here.
Keywords: replacement; mitochondrial replacement; human oocytes; replacement genome ... See more keywords