Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer
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DOI: 10.1371/journal.pcbi.1006596
Abstract: Pancreatic ductal adenocarcinoma (PDAC) has the worst prognosis among solid malignancies and improved therapeutic strategies are needed to improve outcomes. Patient-derived xenografts (PDX) and patient-derived organoids (PDO) serve as promising tools to identify new drugs… read more here.
Keywords: copy number; genomes define; pdac; concordance ... See more keywords