Genomewide Association Study of Statin‐Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.1557
Abstract: Statins can be associated with myopathy. We have undertaken a genomewide association study (GWAS) to discover and validate genetic risk factors for statin‐induced myopathy in a “real‐world” setting. One hundred thirty‐five patients with statin myopathy… read more here.
Keywords: clinical practice; statin induced; association; genomewide association ... See more keywords
Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders"
DOI: 10.1002/mds.27845
Abstract: Several reports have identified different patterns of Parkinson's disease progression in individuals carrying missense variants in GBA or LRRK2 genes. The overall contribution of genetic factors to the severity and progression of Parkinson's disease, however,… read more here.
Keywords: disease; genomewide association; parkinson disease; association study ... See more keywords
Genomewide association study identifies a novel variant associated with tacrolimus trough concentration in Chinese renal transplant recipients
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Science"
DOI: 10.1111/cts.13388
Abstract: Tacrolimus (TAC) is an immunosuppressant widely used in kidney transplantation. TAC displays considerable interindividual variability in pharmacokinetics (PKs). Genetic and clinical factors play important roles in TAC PKs. We enrolled a total of 251 Chinese… read more here.
Keywords: chinese renal; genomewide association; renal transplant; transplant recipients ... See more keywords
Genomewide association analyses of fitness traits in captive‐reared Chinook salmon: Applications in evaluating conservation strategies
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DOI: 10.1111/eva.12599
Abstract: A novel application of genomewide association analyses is to use trait‐associated loci to monitor the effects of conservation strategies on potentially adaptive genetic variation. Comparisons of fitness between captive‐ and wild‐origin individuals, for example, do… read more here.
Keywords: associated loci; trait associated; conservation; genomewide association ... See more keywords
Genomewide association of male reproductive traits in Aksaray Malakli dogs
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DOI: 10.1111/rda.13302
Abstract: Male reproductive parameters are often used for the functional examination and evaluation of predicted genetic values for future aspects. However, these traits are relatively reliable until the measurable effects are expressed on desired traits. Therefore,… read more here.
Keywords: association male; association; genomewide association; reproductive traits ... See more keywords
Genomewide association mapping and pathway analysis of meat tenderness in Polled Nellore cattle.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of animal science"
DOI: 10.2527/jas.2016.1348
Abstract: Brazil is one of the world's largest beef exporters, although the product has a low price due to quality issues. The meat exported by Brazil is considered medium and low quality by international buyers, mainly… read more here.
Keywords: analysis; polled nellore; genomewide association; meat tenderness ... See more keywords