Comparative genomic analysis of carboxylesterase genes in Tenebrio molitor and other four tenebrionids.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21967
Abstract: Carboxylesterases (COEs) have various functions in wide taxons of organisms. In insects, COEs are important enzymes involved in the hydrolysis of a variety of ester-containing xenobiotics, neural signal transmission, pheromone degradation, and reproductive development. Understanding… read more here.
Keywords: comparative genomic; molitor; insects; genomic analysis ... See more keywords
Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function
Sign Up to like & getrecommendations! Published in 2020 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22365
Abstract: Bronchodilator (BD) drugs are commonly prescribed for treatment and management of obstructive lung function present with diseases such as asthma. Administration of BD medication can partially or fully restore lung function as measured by pulmonary… read more here.
Keywords: genomic analysis; integrative genomic; genetics; function ... See more keywords
Genomic analysis reveals a rapid spread and predominance of lambda (C.37) SARS‐COV‐2 lineage in Peru despite circulation of variants of concern
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27261
Abstract: The pandemic generated by SARS‐Cov‐2 has caused a large number of cases and deaths in the world, but South America has been one of the continents that were most hard hit. The appearance of new… read more here.
Keywords: lambda; lineage; variants concern; concern ... See more keywords
Genomic analysis of high copy-number sequences for the targeted detection of Listeria species using a flow-through surveillance system.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of microbiology"
DOI: 10.1007/s00203-021-02388-2
Abstract: The bacterial foodborne pathogen Listeria monocytogenes has been implicated in fresh produce outbreaks with a significant economic impact. Given that L. monocytogenes is widespread in the environment, food production facilities constantly monitor for the presence… read more here.
Keywords: detection; system; listeria; high copy ... See more keywords
Comparative genomic analysis of Pseudomonas aeruginosa phage PaMx25 reveals a novel siphovirus group related to phages infecting hosts of different taxonomic classes
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Virology"
DOI: 10.1007/s00705-017-3366-5
Abstract: Bacteriophages (phages) are estimated to be the most abundant and diverse entities in the biosphere harboring vast amounts of novel genetic information. Despite the genetic diversity observed, many phages share common features, such as virion… read more here.
Keywords: pseudomonas aeruginosa; phage; aeruginosa phage; analysis pseudomonas ... See more keywords
Genomic analysis of three Clostridioides difficile isolates from urban water sources.
Sign Up to like & getrecommendations! Published in 2019 at "Anaerobe"
DOI: 10.1016/j.anaerobe.2019.01.002
Abstract: We investigated inflow of a wastewater treatment plant and sediment of an urban lake for the presence of Clostridioides difficile by cultivation and PCR. Among seven colonies we sequenced the complete genomes of three: two… read more here.
Keywords: three clostridioides; difficile isolates; clostridioides difficile; analysis three ... See more keywords
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.02.033
Abstract: Summary Cholangiocarcinoma (CCA) is an aggressive malignancy of the bile ducts, with poor prognosis and limited treatment options. Here, we describe the integrated analysis of somatic mutations, RNA expression, copy number, and DNA methylation by… read more here.
Keywords: integrative genomic; idh mutant; cholangiocarcinoma; expression ... See more keywords
Comprehensive Genomic Analysis Reveals that the Pioneering Function of FOXA1 Is Independent of Hormonal Signaling
Sign Up to like & getrecommendations! Published in 2019 at "Cell Reports"
DOI: 10.1016/j.celrep.2019.02.036
Abstract: Summary Considerable work has linked hormone receptors, such as estrogen receptor-alpha (ER), with the pioneer factor FOXA1. Altered FOXA1 levels contribute to endocrine-resistant breast cancer, where it maintains ER-chromatin interactions, even in contexts in which… read more here.
Keywords: analysis reveals; comprehensive genomic; foxa1 binding; foxa1 ... See more keywords
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical colorectal cancer"
DOI: 10.1016/j.clcc.2019.02.008
Abstract: BACKGROUND The diagnosis of colorectal cancer (CRC) is routinely accomplished through histopathologic examination. Prognostic information and treatment decisions are mainly determined by TNM classification, first defined in 1968. In the last decade, patient-specific CRC genomic… read more here.
Keywords: analysis workflow; oncology; colorectal cancer; idea ... See more keywords
Genomic analysis and lactose transporter expression in Kluyveromyces marxianus CCT 7735.
Sign Up to like & getrecommendations! Published in 2019 at "Fungal biology"
DOI: 10.1016/j.funbio.2019.06.004
Abstract: Kluyveromyces marxianus CCT 7735 has been used to produce ethanol, aromatic compounds, enzymes and heterologous proteins besides assimilates lactose as carbon source. Its genome has 10.7 Mb and encodes 4787 genes distributed in 8 nuclear chromosomes… read more here.
Keywords: expression; cct 7735; marxianus cct; lac12 genes ... See more keywords
Comparative genomic analysis reveals the evolution and environmental adaptation of Acinetobacter johnsonii.
Sign Up to like & getrecommendations! Published in 2021 at "Gene"
DOI: 10.1016/j.gene.2021.145985
Abstract: Genome plasticity is a key determinant that Acinetobacter johnsonii could widely distribute in natural and clinical environments. However, little attention has been paid to figure out the changes in the genome during A. johnsonii's evolution.… read more here.
Keywords: acinetobacter johnsonii; johnsonii; genomic analysis; comparative genomic ... See more keywords