The 1000 Chinese Indigenous Pig Genomes Project provides insights into the genomic architecture of pigs
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-54471-z
Abstract: Pigs play a central role in human livelihoods in China, but a lack of systematic large-scale whole-genome sequencing of Chinese domestic pigs has hindered genetic studies. Here, we present the 1000 Chinese Indigenous Pig Genomes… read more here.
Keywords: pig genomes; genomic architecture; indigenous pig; pig ... See more keywords
Deconstructing and targeting the genomic architecture of human neurodegeneration
Sign Up to like & getrecommendations! Published in 2018 at "Nature Neuroscience"
DOI: 10.1038/s41593-018-0240-z
Abstract: The field of neurodegenerative disease research has seen tremendous advances over the last two decades as new technologies and analytic methods have enabled well-powered human genomic studies. Driven first by genetic studies and more recently… read more here.
Keywords: genomic architecture; targeting genomic; architecture human; disease ... See more keywords
The genomic architecture of antimalarial drug resistance
Sign Up to like & getrecommendations! Published in 2019 at "Briefings in Functional Genomics"
DOI: 10.1093/bfgp/elz008
Abstract: Abstract Plasmodium falciparum and Plasmodium vivax, the two protozoan parasite species that cause the majority of cases of human malaria, have developed resistance to nearly all known antimalarials. The ability of malaria parasites to develop… read more here.
Keywords: genomic architecture; drug resistance; antimalarial drug; resistance ... See more keywords
Linked-Read Sequencing of Eight Falcons Reveals a Unique Genomic Architecture in Flux
Sign Up to like & getrecommendations! Published in 2022 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evac090
Abstract: Falcons are diverse birds of cultural and economic importance. They have undergone major lineage-specific chromosomal rearrangements, resulting in greatly-reduced chromosome counts relative to other birds. Here, we use 10X Genomics linked reads to provide new… read more here.
Keywords: falcon genomes; linked read; chromosomal rearrangements; genomic architecture ... See more keywords
Genomic Architecture Predicts Tree Topology, Population Structuring, and Demographic History in Amazonian Birds
Sign Up to like & getrecommendations! Published in 2024 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evae002
Abstract: Abstract Geographic barriers are frequently invoked to explain genetic structuring across the landscape. However, inferences on the spatial and temporal origins of population variation have been largely limited to evolutionary neutral models, ignoring the potential… read more here.
Keywords: genomic architecture; topology; population structuring; history ... See more keywords
Common Stress Transcriptome Analysis Reveals Functional and Genomic Architecture Differences Between Early and Delayed Response Genes
Sign Up to like & getrecommendations! Published in 2017 at "Plant and Cell Physiology"
DOI: 10.1093/pcp/pcx002
Abstract: To identify the similarities among responses to diverse environmental stresses, we analyzed the transcriptome response of rice roots to three rhizotoxic perturbations (chromium, ferulic acid and mercury) and identified common early-transient, early-constant and delayed gene… read more here.
Keywords: genomic architecture; response; delayed response; early transient ... See more keywords
Genomic architecture of supergenes: connecting form and function
Sign Up to like & getrecommendations! Published in 2022 at "Philosophical Transactions of the Royal Society B: Biological Sciences"
DOI: 10.1098/rstb.2021.0192
Abstract: Supergenes are tightly linked sets of loci that are inherited together and control complex phenotypes. While classical supergenes—governing traits such as wing patterns in Heliconius butterflies or heterostyly in Primula—have been studied since the Modern… read more here.
Keywords: form function; connecting form; genomic architecture; supergenes connecting ... See more keywords
Genomic architecture and functional effects of potential human inversion supergenes
Sign Up to like & getrecommendations! Published in 2022 at "Philosophical Transactions of the Royal Society B: Biological Sciences"
DOI: 10.1098/rstb.2021.0209
Abstract: Supergenes are involved in adaptation in multiple organisms, but they are little known in humans. Genomic inversions are the most common mechanism of supergene generation and maintenance. Here, we review the information about two large… read more here.
Keywords: potential human; functional effects; effects potential; inversion ... See more keywords
Genomic architecture underlying morphological and physiological adaptation to high elevation in a songbird
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Ecology"
DOI: 10.1111/mec.16875
Abstract: Organisms often acquire physiological and morphological modifications to conquer ecological challenges when colonizing new environments which lead to their adaptive evolution. However, deciphering the genomic mechanism of ecological adaptation is difficult because ecological environments are… read more here.
Keywords: songbird; adaptation; genomic architecture; physiological adaptation ... See more keywords
Genomic architecture of a genetically assimilated seasonal color pattern
Sign Up to like & getrecommendations! Published in 2020 at "Science"
DOI: 10.1126/science.aaz3017
Abstract: Untangling the genetics of plasticity The common buckeye butterfly, Junonia coenia, exhibits plastic coloration; it has two color morphs, light tan and dark red, that depend on day length and temperature. By selecting for more… read more here.
Keywords: genomic architecture; trait; color; assimilated seasonal ... See more keywords
Genomic architecture of egg mimicry and its consequences for speciation in parasitic cuckoos.
Sign Up to like & getrecommendations! Published in 2025 at "Science"
DOI: 10.1126/science.adt9355
Abstract: Host-parasite arms races facilitate rapid evolution and can fuel speciation. Cuculus cuckoos are deceptive egg mimics that exhibit a broad diversity of counterfeit egg phenotypes, representing host-adapted subpopulations (gentes). Genome analysis of 298 common (Cuculus… read more here.
Keywords: speciation; cuckoos; architecture egg; genomic architecture ... See more keywords