Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multicenter study
Sign Up to like & getrecommendations! Published in 2020 at "Haematologica"
DOI: 10.3324/haematol.2019.239947
Abstract: Complex karyotype identified by chromosome-banding analysis has been shown to have prognostic value in chronic lymphocytic leukemia (CLL). Genomic arrays offer high-resolution genomewide detection of copy-number alterations (CNA) and could therefore be well equipped to… read more here.
Keywords: risk; lymphocytic leukemia; genomic arrays; chronic lymphocytic ... See more keywords
Genomic arrays for the identification of high-risk chronic lymphocytic leukemia: ready for prime time?
Sign Up to like & getrecommendations! Published in 2021 at "Haematologica"
DOI: 10.3324/haematol.2020.264689
Abstract: Hematopoietic tumors develop through the acquisition of multiple molecular cytogenetic lesions, which confer growth advantage to the neoplastic cells, favoring the emergence of clones resistant to treatment. Not surprisingly, a high number of chromosome aberrations… read more here.
Keywords: complex karyotype; lymphocytic leukemia; genomic arrays; chronic lymphocytic ... See more keywords