Genomic changes of chromosomes 8p23.1 and 1q21: Novel mutations in malignant mesothelioma.
Sign Up to like & getrecommendations! Published in 2018 at "Lung cancer"
DOI: 10.1016/j.lungcan.2018.10.012
Abstract: INTRODUCTION Malignant mesothelioma is an aggressive malignancy of the thoracic cavity caused by prior asbestos exposure. In the peritoneum the mesothelioma is an extremely rare condition. In the present preliminary study, high-resolution array-comparative genomic hybridization… read more here.
Keywords: changes chromosomes; mesothelioma; genomic changes; 8p23 1q21 ... See more keywords
A-to-I RNA editing contributes to the persistence of predicted damaging mutations in populations
Sign Up to like & getrecommendations! Published in 2019 at "Genome Research"
DOI: 10.1101/gr.246033.118
Abstract: Adenosine-to-inosine (A-to-I) RNA editing is a very common co-/posttranscriptional modification that can lead to A-to-G changes at the RNA level and compensate for G-to-A genomic changes to a certain extent. It has been shown that… read more here.
Keywords: genomic changes; rna; nonsynonymous editing; editing contributes ... See more keywords
Exploiting the Molecular Basis of Oesophageal Cancer for Targeted Therapies and Biomarkers for Drug Response: Guiding Clinical Decision-Making
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10102359
Abstract: Worldwide, oesophageal cancer is the sixth leading cause of deaths related to cancer and represents a major health concern. Sub-Saharan Africa is one of the regions of the world with the highest incidence and mortality… read more here.
Keywords: exploiting molecular; genomic changes; treatment; oesophageal cancer ... See more keywords