Perinatal outcomes and genomic characteristics of fetal copy number variants: An individual record linkage study of 713 pregnancies
Sign Up to like & getrecommendations! Published in 2023 at "Prenatal Diagnosis"
DOI: 10.1002/pd.6305
Abstract: To determine the perinatal outcomes of fetuses diagnosed with a pathogenic copy number variant (CNV) or variant of uncertain significance (VUS); and to characterize these variants in terms of testing indication, genomic location, size, and… read more here.
Keywords: outcomes genomic; genomic characteristics; copy number; perinatal outcomes ... See more keywords
First detection and genomic characteristics of bovine torovirus in dairy calves in China
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DOI: 10.1007/s00705-020-04657-9
Abstract: Bovine torovirus (BToV) is a diarrhea-causing pathogen. In this study, 92 diarrheic fecal samples from five farms in four provinces in China were collected and tested for BToV using a RT-PCR assay, and 21.73% samples… read more here.
Keywords: bovine torovirus; first detection; amino acid; btov ... See more keywords
Genomic characteristics of clinical important ST11 Klebsiella pneumoniae worldwide.
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DOI: 10.1016/j.jgar.2020.03.023
Abstract: BACKGROUND ST11 Klebsiella pneumoniae is among the most important clinical pathogen in China, and KL47 and KL64 are the dominant K-types of these strains. Understanding the genomic characteristics of these strains would be critical to… read more here.
Keywords: st11; pneumoniae; genomic characteristics; klebsiella pneumoniae ... See more keywords
Genomic characteristics and phylogenetic relationships of Cutibacterium acnes breast milk isolates
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DOI: 10.1186/s12866-024-03717-3
Abstract: Cutibacterium acnes is one of the most commonly found microbes in breast milk. However, little is known about the genomic characteristics of C. acnes isolated from breast milk. In this study, the sequencing and assembly… read more here.
Keywords: cutibacterium acnes; breast milk; milk isolates; milk ... See more keywords
Genomic characteristics and prognostic correlations in Chinese multiple myeloma patients
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DOI: 10.1186/s12920-025-02116-5
Abstract: Multiple myeloma (MM) is a hematologic malignancy characterized by the proliferation of abnormal clonal plasma cells in the bone marrow. The heterogeneity in Chinese MM populations remains underexplored. We conducted whole-exome sequencing (WES) on 241… read more here.
Keywords: correlations chinese; multiple myeloma; characteristics prognostic; prognostic correlations ... See more keywords
Genomic characteristics associated with clinical activity of rucaparib in patients (pts) with BRCA1 or BRCA2 (BRCA)-mutated metastatic castration-resistant prostate cancer (mCRPC).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.6_suppl.178
Abstract: 178Background: The phase 2 TRITON2 study (NCT02952534) is evaluating the PARP inhibitor rucaparib in pts with mCRPC and a deleterious germline or somatic alteration in BRCA (BRCA pts) or 1 of 13 ot... read more here.
Keywords: clinical activity; associated clinical; rucaparib; genomic characteristics ... See more keywords
Genomic characteristics and their clinical significance in a large cohort of biliary tract cancers with more than 4,000 patients.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.e16285
Abstract: e16285 Background: Biliary tract cancers (BTCs) are mainly divided into cholangiocarcinoma (CHOL) and gallbladder cancer (GBC). Genomic characteristics of advanced BTCs are still needed to be investigated in large cohorts. The association of genomic alterations… read more here.
Keywords: advanced btcs; gbc; chol; biliary tract ... See more keywords
Large language models (LLMs) for inferring genomic characteristics and facilitating genomic literacy in prostate cancer (PCa) patients.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.5_suppl.261
Abstract: 261 Background: Clinicians use next-generation sequencing (NGS) to tailor targeted treatments for PCa patients. However, the results are often available in unstructured formats and are saturated with technical jargon, making them inaccessible for patients. Therefore,… read more here.
Keywords: large language; pca patients; unstructured reports; language ... See more keywords
In silico evaluation of genomic characteristics of Streptococcus infantarius subsp. infantarius for application in fermentations.
Sign Up to like & getrecommendations! Published in 2022 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202220211447
Abstract: This study aims to evaluate the in silico genomic characteristics of Streptococcus infantarius subsp. infantarius, isolated from Coalho cheese from Paraíba, Brazil, with a view to application in lactic fermentations. rRNA sequences from the 16S… read more here.
Keywords: characteristics streptococcus; genomic characteristics; subsp infantarius; infantarius subsp ... See more keywords
Genomic characteristics in Chinese non-small cell lung cancer patients and its value in prediction of postoperative prognosis.
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DOI: 10.21037/tlcr-19-664
Abstract: Background The genomic profile of non-small cell lung cancer (NSCLC) in Asians is distinct from that of Caucasians, but comprehensive genetic profiling reports have been limited for Asian patients. We aimed to elucidate genomic characteristics… read more here.
Keywords: lung cancer; genomic characteristics; non small; cell ... See more keywords
Genomic Characteristics of a Carbapenem-Resistant Klebsiella pneumoniae Co-Carrying blaNDM-5 and blaKPC-2 Capsular Type KL25 Recovered from a County Level Hospital in China
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DOI: 10.2147/idr.s479560
Abstract: Background Hypervirulent carbapenem-resistant K. pneumoniae (hv-CRKP) has been spreading rapidly worldwide. Here, we investigated the genomic characteristics of ST11 K. pneumoniae isolate SM117 with capsular serotype KL25, co-carrying blaNDM-5, two copies of blaKPC-2 and multiple… read more here.
Keywords: china; pneumoniae; type; kl25 ... See more keywords