Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Communications"
DOI: 10.1002/cac2.12372
Abstract: Neuroendocrine carcinomas of the gastrointestinal tract (GI‐NECs) remain a disease of grim prognosis with limited therapeutic options. Their molecular characteristics are still undefined. This study aimed to explore the underlying genetic basis and heterogeneity of… read more here.
Keywords: carcinomas gastrointestinal; neuroendocrine carcinomas; genomic characterization; characterization reveals ... See more keywords
Genomic characterization and phylogenetic analysis of SARS‐COV‐2 in Italy
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25794
Abstract: Abstract This report describes the isolation, molecular characterization, and phylogenetic analysis of the first three complete genomes of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) isolated from three patients involved in the first outbreak of… read more here.
Keywords: sars cov; phylogenetic analysis; characterization phylogenetic; genomic characterization ... See more keywords
Genomic characterization of circoviruses associated with acute gastroenteritis in minks in northeastern China
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DOI: 10.1007/s00705-018-3908-5
Abstract: Mink circovirus (MiCV), a virus that was newly discovered in 2013, has been associated with enteric disease. However, its etiological role in acute gastroenteritis is unclear, and its genetic characteristics are poorly described. In this… read more here.
Keywords: batcv; genomic characterization; acute gastroenteritis; gastroenteritis ... See more keywords
Genomic characterization of Malus domestica virus A (MdoVA), a novel velarivirus infecting apple
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Virology"
DOI: 10.1007/s00705-019-04478-5
Abstract: Screening of apple samples using a high-throughput sequencing (HTS) approach led to the discovery of a novel virus, tentatively named “Malus domestica virus A” (MdoVA). Its genomic organisation and phylogenetic relationship showed relatedness to viruses… read more here.
Keywords: virus mdova; domestica virus; genomic characterization; malus domestica ... See more keywords
Genomic characterization of the nucleus for conservation of the Chino Santandereano breed using SNP markers.
Sign Up to like & getrecommendations! Published in 2021 at "Tropical animal health and production"
DOI: 10.1007/s11250-021-02936-4
Abstract: The Chino Santandereano (CHS) creole cattle breed has undergone an adaptation process of more than 500 years to the Colombian mountainous tropics. Despite its advantages, the breed has been replaced by specialized cattle that put it… read more here.
Keywords: chino santandereano; nucleus conservation; genomic characterization; conservation ... See more keywords
Comparative genomic characterization of melanoma of known and unknown primary
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-021-02629-2
Abstract: This study aims to genomically characterize melanoma of unknown primary (MUP) in comparison to melanomas of cutaneous primary (MCP). Eligible cases were collected from the MSK-IMPACT™ Clinical Sequencing Cohort published in the cBioPortal database. Genomic… read more here.
Keywords: melanoma known; characterization melanoma; genomic characterization; known unknown ... See more keywords
Genomic Characterization of the First Parechovirus in Bats
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DOI: 10.1007/s12250-019-00108-1
Abstract: As important hosts for several pathogenic viruses, bats harbor viruses from almost all families of vertebrate viruses, including several genera of family Picornaviridae, including Hepatovirus, Kobuvirus, Crohivirus, and Sapelovirus ( Drexler et al. 2015 ;… read more here.
Keywords: parechovirus bats; characterization first; first parechovirus; genomic characterization ... See more keywords
Further genomic characterization of pineapple mealybug wilt-associated viruses using high-throughput sequencing
Sign Up to like & getrecommendations! Published in 2020 at "Tropical Plant Pathology"
DOI: 10.1007/s40858-019-00330-y
Abstract: In this study, we describe the further genomic characterization of several pineapple mealybug wilt-associated virus (PMWaV) members of the genus Ampelovirus , family Closteroviridae , using high-throughput sequencing (HTS). PMWaV-2 is a necessary factor in… read more here.
Keywords: etiology; genomic characterization; mealybug wilt; characterization ... See more keywords
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients
Sign Up to like & getrecommendations! Published in 2022 at "Cell"
DOI: 10.1016/j.cell.2022.01.003
Abstract: Metastatic progression is the main cause of death in cancer patients, whereas the underlying genomic mechanisms driving metastasis remain largely unknown. Here, we assembled MSK-MET, a pan-cancer cohort of over 25,000 patients with metastatic diseases.… read more here.
Keywords: cancer; genomic characterization; metastatic patterns; 000 patients ... See more keywords
Genomic characterization of three GES-producing Enterobacterales isolated in the Czech Republic.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2022.02.016
Abstract: BACKGROUND The aim of the study is to characterize the genomic features of three GES-producing Enterobacterales isolates from Czech Hospitals. METHODS In 2020, during a routine screening of the hospital's surfaces in Prague General Hospital,… read more here.
Keywords: genomic characterization; ges producing; characterization three; three ges ... See more keywords
Isolation and genomic characterization of P.A-5, a novel virulent bacteriophage against Enterobacter hormaechei.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2021.104767
Abstract: Enterobacter hormaechei is a foodborne pathogen responsible for neonatal sepsis in humans and respiratory disease in animals. In this work, a new virulent phage (P.A-5) infecting E. hormaechei was isolated from domestic sewage samples and… read more here.
Keywords: characterization novel; isolation genomic; hormaechei; genomic characterization ... See more keywords