A pipeline for effectively developing highly polymorphic simple sequence repeats markers based on multi‐sample genomic data
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.8705
Abstract: Abstract Simple sequence repeats (SSRs) are widely used genetic markers in ecology, evolution, and conservation even in the genomics era, while a general limitation to their application is the difficulty of developing polymorphic SSR markers.… read more here.
Keywords: simple sequence; highly polymorphic; sequence repeats; genomic data ... See more keywords
The Medicago truncatula Genome: Genomic Data Availability.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8633-0_3
Abstract: Medicago truncatula emerged in 1990 as a model for legumes, comprising the third largest land plant family. Most legumes form symbiotic nitrogen-fixing root nodules with compatible soil bacteria and thus are important contributors to the… read more here.
Keywords: data availability; truncatula genome; genomic data; genome genomic ... See more keywords
A fast genomic selection approach for large genomic data
Sign Up to like & getrecommendations! Published in 2017 at "Theoretical and Applied Genetics"
DOI: 10.1007/s00122-017-2887-3
Abstract: Key messageWe propose a novel computational method for genomic selection that combines identical-by-state (IBS)-based Haseman–Elston (HE) regression and best linear prediction (BLP), called HE-BLP.AbstractGenomic best linear unbiased prediction (GBLUP) has been widely used in whole-genome… read more here.
Keywords: regression; genomic selection; method; genomic data ... See more keywords
Australia: regulating genomic data sharing to promote public trust
Sign Up to like & getrecommendations! Published in 2018 at "Human Genetics"
DOI: 10.1007/s00439-018-1914-z
Abstract: The regulation of genomic data sharing in Australia is a confusing mix of common law, legislation, ethical guidelines, and codes of practice. Beyond privacy laws, which only apply to genomic data that meets the definition… read more here.
Keywords: research; data sharing; public trust; genomic data ... See more keywords
Expanding Access to Large-Scale Genomic Data While Promoting Privacy: A Game Theoretic Approach.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2016.12.002
Abstract: Emerging scientific endeavors are creating big data repositories of data from millions of individuals. Sharing data in a privacy-respecting manner could lead to important discoveries, but high-profile demonstrations show that links between de-identified genomic data… read more here.
Keywords: expanding access; genomic data; game theoretic; approach ... See more keywords
HIPAA's Individual Right of Access to Genomic Data: Reconciling Safety and Civil Rights.
Sign Up to like & getrecommendations! Published in 2018 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2017.12.004
Abstract: In 2014, the United States granted individuals a right of access to their own laboratory test results, including genomic data. Many observers feel that this right is in tension with regulatory and bioethical standards designed… read more here.
Keywords: safety; genomic data; civil rights; safety civil ... See more keywords
After the deluge: mining Staphylococcus aureus genomic data for clinical associations and host-pathogen interactions.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in microbiology"
DOI: 10.1016/j.mib.2017.11.014
Abstract: The genome of Staphylococcus aureus has rapidly become one the most frequently sequenced among bacteria, with more than 40000 genome sequences uploaded to public databases. Computational resources required for analysis and quality assessment have lagged… read more here.
Keywords: staphylococcus; staphylococcus aureus; mining staphylococcus; genomic data ... See more keywords
Clinical and genomic data of sars-cov-2 detected in maternal-fetal interface during the first wave of infection in brazil
Sign Up to like & getrecommendations! Published in 2022 at "Microbes and Infection"
DOI: 10.1016/j.micinf.2022.104949
Abstract: Brazil has the highest SARS-CoV-2 case-fatality rate in pregnant women in the Americas. In this study, clinical and virological findings of five mildly symptomatic pregnant women and their infected fetuses/newborns treated at a referral hospital… read more here.
Keywords: pregnant women; sars cov; genomic data; clinical genomic ... See more keywords
Population genomic data reveal extreme geographic subdivision and novel conservation actions for the declining foothill yellow-legged frog
Sign Up to like & getrecommendations! Published in 2018 at "Heredity"
DOI: 10.1038/s41437-018-0097-7
Abstract: Genomic data have the potential to inform high resolution landscape genetic and biological conservation studies that go far beyond recent mitochondrial and microsatellite analyses. We characterize the relationships of populations of the foothill yellow-legged frog,… read more here.
Keywords: foothill yellow; genomic data; conservation; legged frog ... See more keywords
Leveraging European infrastructures to access 1 million human genomes by 2022
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Genetics"
DOI: 10.1038/s41576-019-0156-9
Abstract: Human genomics is undergoing a step change from being a predominantly research-driven activity to one driven through health care as many countries in Europe now have nascent precision medicine programmes. To maximize the value of… read more here.
Keywords: genomic data; human genomes; leveraging european; genomes 2022 ... See more keywords
Responsible, practical genomic data sharing that accelerates research
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Genetics"
DOI: 10.1038/s41576-020-0257-5
Abstract: Data sharing anchors reproducible science, but expectations and best practices are often nebulous. Communities of funders, researchers and publishers continue to grapple with what should be required or encouraged. To illuminate the rationales for sharing… read more here.
Keywords: data sharing; research; responsible practical; sharing accelerates ... See more keywords