Genomic and epigenetic landscapes drive CRISPR-based genome editing in Bifidobacterium
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2205068119
Abstract: Significance Genome engineering in Bifidobacterium remains challenging, despite successful CRISPR deployment in other bacteria, hindering the comprehensive understanding of the molecular mechanisms of health-promoting effects. In this study, we adapted existing CRISPR effectors and editing… read more here.
Keywords: genome editing; drive crispr; bifidobacterium; genomic epigenetic ... See more keywords
Genomic and Epigenetic Advances in Focal Cortical Dysplasia Types I and II: A Scoping Review
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2020.580357
Abstract: Introduction: Focal cortical dysplasias (FCDs) are a group of malformations of cortical development that constitute a common cause of drug-resistant epilepsy, often subjected to neurosurgery, with a suboptimal long-term outcome. The past few years have… read more here.
Keywords: fcd; focal cortical; scoping review; epigenetic advances ... See more keywords