Centralization errors in comparative genomic hybridization array analysis of pituitary tumor samples
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.1002/gcc.22534
Abstract: Reliable interpretation of comparative genomic hybridization array (aCGH) results requires centralization and normalization of the data. We evaluated the reliability of aCGH centralization by comparing aCGH results (with classical centralization‐normalization steps) to fluorescence in situ… read more here.
Keywords: log2 ratios; genomic hybridization; hybridization; comparative genomic ... See more keywords
Non‐invasive prenatal screening versus prenatal diagnosis by array comparative genomic hybridization: a comparative retrospective study
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DOI: 10.1002/pd.5051
Abstract: To calculate the proportion of array comparative genomic hybridization (aCGH) pathogenic results, that would not be detectable by non‐invasive prenatal screening (NIPS). read more here.
Keywords: prenatal screening; invasive prenatal; genomic hybridization; array comparative ... See more keywords
Comparative Genomic Hybridization and Transcriptome Sequencing Reveal Genes with Gain in Acute Lymphoblastic Leukemia: JUP Expression Emerges as a Survival-Related Gene
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12112788
Abstract: Acute lymphoblastic leukemia (ALL) in children or adults is characterized by structural and numeric aberrations in chromosomes; these anomalies strongly correlate with prognosis and clinical outcome. Therefore, this work aimed to identify the genes present… read more here.
Keywords: genomic hybridization; lymphoblastic leukemia; comparative genomic; acute lymphoblastic ... See more keywords
Comparative Genomic Hybridization to Microarrays in Fetuses with High-Risk Prenatal Indications: Polish Experience with 7400 Pregnancies
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13040690
Abstract: The aim of this study was to determine the suitability of the comparative genomic hybridization to microarray (aCGH) technique for prenatal diagnosis, but also to assess the frequency of chromosomal aberrations that may lead to… read more here.
Keywords: detection rate; high risk; comparative genomic; genomic hybridization ... See more keywords
Custom Array Comparative Genomic Hybridization: the Importance of DNA Quality, an Expert Eye, and Variant Validation
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DOI: 10.3390/ijms18030609
Abstract: The presence of false positive and false negative results in the Array Comparative Genomic Hybridization (aCGH) design is poorly addressed in literature reports. We took advantage of a custom aCGH recently carried out to analyze… read more here.
Keywords: quality; genomic hybridization; array comparative; comparative genomic ... See more keywords
Giant Sex Chromosomes in Omophoita Species (Coleoptera, Chrysomelidae): Structural and Evolutionary Relationships Revealed by Zoo-FISH and Comparative Genomic Hybridization (CGH)
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DOI: 10.3390/insects14050440
Abstract: Simple Summary Unlike most beetles that have small XY sex chromosomes, the Oedionychina group (Coleoptera, Alticinae) has atypical sex chromosomes, which are called giant sex chromosomes because they are much larger than the autosomes. There… read more here.
Keywords: comparative genomic; similarity; giant sex; sex ... See more keywords
Determination of genetic aberrations and novel transcripts involved in the pathogenesis of oligodendroglioma using array comparative genomic hybridization and next generation sequencing
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DOI: 10.3892/ol.2018.9811
Abstract: The aim of the present study was to determine the genetic aberrations and novel transcripts, particularly the fusion transcripts, involved in the pathogenesis of low-grade and anaplastic oligodendroglioma. In the present study, tissue samples were… read more here.
Keywords: genetic aberrations; genomic hybridization; oligodendroglioma; aberrations novel ... See more keywords