MicroRNAs play regulatory roles in genomic balance
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202200187
Abstract: Classic genetics studies found that genomic imbalance caused by changing the dosage of part of the genome (aneuploidy) has more detrimental effects than altering the dosage of the whole genome (ploidy). Previous analysis revealed global… read more here.
Keywords: genomic balance; genomic imbalance; expression; play regulatory ... See more keywords
A new case of 17p13.3p13.1 microduplication resulted from unbalanced translocation: clinical and molecular cytogenetic characterization
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DOI: 10.1186/s13039-021-00562-1
Abstract: Copy number gain 17 p13.3p13.1 was detected by chromosomal microarray (CMA) in a girl with developmental/speech delay and facial dysmorphism. FISH studies made it possible to establish that the identified genomic imbalance is the unbalanced… read more here.
Keywords: new case; case 17p13; genomic imbalance; translocation ... See more keywords
Simultaneous detection of genomic imbalance in patients receiving preimplantation genetic testing for monogenic diseases (PGT-M)
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DOI: 10.3389/fgene.2022.976131
Abstract: Background: Preimplantation genetic test for monogenic disorders (PGT-M) has been used to select genetic disease-free embryos for implantation during in vitro fertilization (IVF) treatment. However, embryos tested by PGT-M have risks of harboring chromosomal aneuploidy.… read more here.
Keywords: preimplantation genetic; genomic imbalance; pgt; monogenic diseases ... See more keywords