The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cell Reports"
DOI: 10.1016/j.celrep.2019.04.098
Abstract: Summary The detailed molecular characterization of lethal cancers is a prerequisite to understanding resistance to therapy and escape from cancer immunoediting. We performed extensive multi-platform profiling of multi-regional metastases in autopsies from 10 patients with… read more here.
Keywords: immune landscapes; breast cancer; genomic immune; landscapes lethal ... See more keywords
Genomic and immune infiltration differences between MSI and MSS GI tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.528
Abstract: 528 Background: Dysregulation of DNA mismatch repair pathway can lead to microsatellite instability in many GI tumors, and microsatellite instability is an important diagnostic and prognostic marker. Microsatellite instable (MSI) tumors comprise about 15% of… read more here.
Keywords: msi; msi tumors; immune infiltration; genomic immune ... See more keywords
Genomic and immune intratumor heterogeneity in gastric linitis plastica.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e16518
Abstract: e16518Background: Gastric linitis plastica (LP) is a rare and aggressive type of gastric cancer (GC) for which the genomic landscape and architecture have gone largely undescribed. Methods: 4 LP pa... read more here.
Keywords: linitis plastica; gastric linitis; genomic immune; immune intratumor ... See more keywords
Comprehensive Approach to Genomic and Immune Profiling: Insights of a Real-World Experience in Gynecological Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12081903
Abstract: Gynecological cancer accounts for an elevated incidence worldwide requiring responsiveness regarding its care. The comprehensive genomic approach agrees with the classification of certain tumor types. We evaluated 49 patients with gynecological tumors undergoing high-throughput sequencing… read more here.
Keywords: comprehensive approach; genomic immune; approach genomic; approach ... See more keywords