Comparative genomics analysis of statistically significant genomic islands of Helicobacter pylori strains for better understanding the disease prognosis
Sign Up to like & getrecommendations! Published in 2022 at "Bioscience Reports"
DOI: 10.1042/bsr20212084
Abstract: Abstract Bacterial virulence factors are often located in their genomic islands (GIs). Helicobacter pylori, a highly diverse organism is reported to be associated with several gastrointestinal diseases like, gastritis, gastric cancer (GC), peptic ulcer, duodenal… read more here.
Keywords: better understanding; pylori strains; disease prognosis; virulence ... See more keywords
Genomic islands and their role in fitness traits of two key sepsis-causing bacterial pathogens.
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/elac051
Abstract: To survive and establish a niche for themselves, bacteria constantly evolve. Toward that, they not only insert point mutations and promote illegitimate recombinations within their genomes but also insert pieces of 'foreign' deoxyribonucleic acid, which… read more here.
Keywords: sepsis; islands role; traits two; fitness traits ... See more keywords
Zisland Explorer: detect genomic islands by combining homogeneity and heterogeneity properties
Sign Up to like & getrecommendations! Published in 2017 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbw019
Abstract: Abstract Genomic islands are genomic fragments of alien origin in bacterial and archaeal genomes, usually involved in symbiosis or pathogenesis. In this work, we described Zisland Explorer, a novel tool to predict genomic islands based… read more here.
Keywords: homogeneity heterogeneity; genomic islands; zisland explorer; explorer ... See more keywords
MTGIpick allows robust identification of genomic islands from a single genome
Sign Up to like & getrecommendations! Published in 2018 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbw118
Abstract: Genomic islands (GIs) that are associated with microbial adaptations and carry sequence patterns different from that of the host are sporadically distributed among closely related species. This bias can dominate the signal of interest in… read more here.
Keywords: gis; single genome; mtgipick; mtgipick allows ... See more keywords
Genomic islands 1 and 2 carry multiple antibiotic resistance genes in Pseudomonas aeruginosa ST235, ST253, ST111 and ST175 and are globally dispersed
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkw471
Abstract: family), with the gene cassette aac(30)-II being replaced by aacA4 and catB8 (accession no. CP001938). The K. pneumoniae strain belongs to MLST sequence type 307 (ST307) and harboured a 20 kb plasmid (IncF) that was… read more here.
Keywords: multiple antibiotic; resistance; islands carry; antibiotic resistance ... See more keywords
Sympatric or micro-allopatric speciation in a glacial lake? Genomic islands support neither
Sign Up to like & getrecommendations! Published in 2022 at "National Science Review"
DOI: 10.1093/nsr/nwac291
Abstract: Abstract Apparent cases of sympatric speciation may actually be due to micro-allopatric or micro-parapatric speciation. One way to distinguish between these models is to examine the existence and nature of genomic islands of divergence, wherein… read more here.
Keywords: sympatric speciation; genomic islands; allopatric speciation; speciation ... See more keywords
Multidrug-resistant toxigenic Corynebacterium diphtheriae sublineage 453 with two novel resistance genomic islands
Sign Up to like & getrecommendations! Published in 2023 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000923
Abstract: Antimicrobial therapy is important for case management of diphtheria, but knowledge on the emergence of multidrug-resistance in Corynebacterium diphtheriae is scarce. We report on the genomic features of two multidrug-resistant toxigenic isolates sampled from wounds… read more here.
Keywords: resistant toxigenic; resistance; multidrug resistant; corynebacterium diphtheriae ... See more keywords
Genomic islands of differentiation in two songbird species reveal candidate genes for hybrid female sterility
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Ecology"
DOI: 10.1111/mec.14479
Abstract: Hybrid sterility is a common first step in the evolution of postzygotic reproductive isolation. According to Haldane's Rule, it affects predominantly the heterogametic sex. While the genetic basis of hybrid male sterility in organisms with… read more here.
Keywords: sterility; genetic basis; hybrid female; female sterility ... See more keywords
Linked selection, differential introgression and recombination rate variation promote heterogeneous divergence in a pair of yellow croakers
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Ecology"
DOI: 10.1111/mec.16693
Abstract: Understanding the mechanisms underlying heterogeneous genomic divergence is of particular interest in evolutionary biology. Highly differentiated genomic regions, known as genomic islands, often evolve between diverging lineages. These genomic islands may be related to selection… read more here.
Keywords: recombination rate; divergence; genomic islands; linked selection ... See more keywords
Systematic Discovery of a New Catalogue of Tyrosine-Type Integrases in Bacterial Genomic Islands
Sign Up to like & getrecommendations! Published in 2023 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.01738-22
Abstract: Site-specific recombinases or integrases have high specificity for DNA large fragment integration, which is urgently needed for gene editing. However, known integrases are not sufficient for meeting multiple integrations. ABSTRACT Site-specific recombinases (integrases) can mediate… read more here.
Keywords: tyrosine type; site; integration; genomic islands ... See more keywords
Comparative analysis reveals the Genomic Islands in Pasteurella multocida population genetics: on Symbiosis and adaptability
Sign Up to like & getrecommendations! Published in 2018 at "BMC Genomics"
DOI: 10.1186/s12864-018-5366-6
Abstract: BackgroundPasteurella multocida (P. multocida) is a widespread opportunistic pathogen that infects human and various animals. Genomic Islands (GIs) are one of the most important mobile components that quickly help bacteria acquire large fragments of foreign… read more here.
Keywords: multocida; pan genome; genetics; population genetics ... See more keywords