Heterogeneity and genomic loci of ubiquitous transgenic Cre reporter lines in zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.499
Abstract: The most‐common strategy for zebrafish Cre/lox‐mediated lineage labeling experiments combines ubiquitously expressed, lox‐based Switch reporter transgenes with tissue‐specific Cre or 4‐OH‐Tamoxifen‐inducible CreERT2 driver lines. Although numerous Cre driver lines have been produced, only a few… read more here.
Keywords: reporter lines; cre; reporter; heterogeneity genomic ... See more keywords
Genomic loci modulating retinal ganglion cell death following elevated IOP in the mouse
Sign Up to like & getrecommendations! Published in 2018 at "Experimental eye research"
DOI: 10.1016/j.exer.2017.12.013
Abstract: &NA; The present study was designed to identify genomic loci modulating the susceptibility of retinal ganglion cells (RGC) to elevated intraocular pressure (IOP) in the BXD recombinant inbred mouse strain set. IOP was elevated by… read more here.
Keywords: death; elevated iop; genomic loci; loci modulating ... See more keywords
Catalytic-Independent Functions of PARP-1 Determine Sox2 Pioneer Activity at Intractable Genomic Loci.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular cell"
DOI: 10.1016/j.molcel.2017.01.017
Abstract: Pioneer transcription factors (TFs) function as genomic first responders, binding to inaccessible regions of chromatin to promote enhancer formation. The mechanism by which pioneer TFs gain access to chromatin remains an important unanswered question. Here… read more here.
Keywords: pioneer activity; genomic loci; intractable genomic; activity ... See more keywords
Pgltools: a genomic arithmetic tool suite for manipulation of Hi-C peak and other chromatin interaction data
Sign Up to like & getrecommendations! Published in 2017 at "BMC Bioinformatics"
DOI: 10.1186/s12859-017-1621-0
Abstract: BackgroundGenomic interaction studies use next-generation sequencing (NGS) to examine the interactions between two loci on the genome, with subsequent bioinformatics analyses typically including annotation, intersection, and merging of data from multiple experiments. While many file… read more here.
Keywords: tool suite; tool; genomic loci; interaction ... See more keywords