A community resource for paired genomic and metabolomic data mining
Sign Up to like & getrecommendations! Published in 2021 at "Nature Chemical Biology"
DOI: 10.1038/s41589-020-00724-z
Abstract: Genomics and metabolomics are widely used to explore specialized metabolite diversity. The Paired Omics Data Platform is a community initiative to systematically document links between metabolome and (meta)genome data, aiding identification of natural product biosynthetic… read more here.
Keywords: community resource; genomic metabolomic; community; resource paired ... See more keywords
Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed Culture and Elicitation Conditions for the Production of Antimicrobial Compounds
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DOI: 10.3390/biom10050673
Abstract: Concern about finding new antibiotics against drug-resistant pathogens is increasing every year. Antarctic bacteria have been proposed as an unexplored source of bioactive metabolites; however, most biosynthetic gene clusters (BGCs) producing secondary metabolites remain silent… read more here.
Keywords: antarctic bacteria; elicitation; elicitation conditions; genomic metabolomic ... See more keywords
Genomic and Metabolomic Investigation of a Rhizosphere Isolate Streptomyces netropsis WLXQSS-4 Associated with a Traditional Chinese Medicine
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DOI: 10.3390/molecules26082147
Abstract: Rhizosphere microorganisms play important ecological roles in promoting herb growth and producing abundant secondary metabolites. Studies on the rhizosphere microbes of traditional Chinese medicines (TCMs) are limited, especially on the genomic and metabolic levels. In… read more here.
Keywords: netropsis wlxqss; medicine; traditional chinese; genomic metabolomic ... See more keywords
Applications and Restrictions of Integrated Genomic and Metabolomic Screening: An Accelerator for Drug Discovery from Actinomycetes?
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DOI: 10.3390/molecules26185450
Abstract: Since the golden age of antibiotics in the 1950s and 1960s actinomycetes have been the most prolific source for bioactive natural products. However, the number of discoveries of new bioactive compounds decreases since decades. New… read more here.
Keywords: genomic metabolomic; applications restrictions; discovery; metabolomic screening ... See more keywords