Differences in genomic patterns and clinical outcomes between African-American and White patients with myelodysplastic syndromes
Sign Up to like & getrecommendations! Published in 2017 at "Blood Cancer Journal"
DOI: 10.1038/bcj.2017.82
Abstract: African-American (AA) patients have a younger age at diagnosis and worse outcomes compared to Whites (WTs) across many cancers, including acute myeloid and acute lymphoblastic leukemias.1, 2, 3 Although inferior outcomes for AAs compared to… read more here.
Keywords: genomic patterns; differences genomic; disease; cancer ... See more keywords
Genomic Patterns of Homozygosity in Chinese Local Cattle
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DOI: 10.1038/s41598-019-53274-3
Abstract: Genome-wide single nucleotide polymorphism (SNP) arrays can be used to explore homozygosity segments, where two haplotypes inherited from the parents are identical. In this study, we identified a total of 27,358 runs of homozygosity (ROH)… read more here.
Keywords: genomic patterns; chinese local; homozygosity chinese; local cattle ... See more keywords
Germline genomic patterns are associated with cancer risk, oncogenic pathways, and clinical outcomes
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.aba4905
Abstract: Germline variants when organized as genomic patterns are associated with cancer risk, oncogenic pathways, and clinical outcomes. There is an ongoing debate on the importance of genetic factors in cancer development, where gene-centered cancer predisposition… read more here.
Keywords: genomic patterns; clinical outcomes; cancer risk; cancer ... See more keywords