Multikernel linear mixed model with adaptive lasso for complex phenotype prediction.
Sign Up to like & getrecommendations! Published in 2020 at "Statistics in medicine"
DOI: 10.1002/sim.8477
Abstract: Linear mixed models (LMMs) and their extensions have been widely used for high-dimensional genomic data analyses. While LMMs hold great promise for risk prediction research, the high dimensionality of the data and different effect sizes… read more here.
Keywords: multikernel linear; genomic regions; adaptive lasso; model ... See more keywords
Genome-wide association mapping of genomic regions associated with phenotypic traits in Canadian western spring wheat
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Breeding"
DOI: 10.1007/s11032-017-0741-6
Abstract: We recently reported genomic regions associated with resistance to four wheat diseases and insensitivity to three Pyrenophora tritici-repentis toxins in an association mapping panel consisting of 81 diverse Canadian western spring wheat (Triticum aestivum L.)… read more here.
Keywords: regions associated; spring wheat; wheat; genomic regions ... See more keywords
Identification of genomic regions harboring diversity between Holstein and two local endangered breeds, Modenese and Maremmana
Sign Up to like & getrecommendations! Published in 2018 at "Livestock Science"
DOI: 10.1016/j.livsci.2018.07.011
Abstract: Abstract The preservation of genetic diversity in farm animals is important to cope with future challenges like climate changes and different production environments. The knowledge of the genes making the endangered breeds different from the… read more here.
Keywords: diversity; identification genomic; genomic regions; holstein two ... See more keywords
Analysis of aroma-related volatile compounds affected by ‘Ginsen Makuwa’ genomic regions introgressed in ‘Vedrantais’ melon background
Sign Up to like & getrecommendations! Published in 2021 at "Scientia Horticulturae"
DOI: 10.1016/j.scienta.2020.109664
Abstract: Abstract Volatile profile of melon fruit from 25 introgression lines (ILs), developed by introgressing specific genomic regions from the Japanese cultivar ‘Ginsen makuwa’ (MAK) into the ‘Charentais’ recurrent genetic background of the cultivar ‘Vedrantais’ (VED),… read more here.
Keywords: melon; mak; genomic regions; background ... See more keywords
Corrigendum: L1-associated genomic regions are deleted in somatic cells of the healthy human brain
Sign Up to like & getrecommendations! Published in 2017 at "Nature Neuroscience"
DOI: 10.1038/nn1017-1427a
Abstract: Nat. Neurosci. 19, 1583–1591 (2016); published online 12 September 2016; corrected after print 13 July 2017 In the version of this article initially published, NIH grant T32 CA009370 to F.H.G. was missing from the Acknowledgments.… read more here.
Keywords: deleted somatic; regions deleted; genomic regions; corrigendum associated ... See more keywords
Multi-locus genome-wide association studies (ML-GWAS) reveal novel genomic regions associated with seedling and adult plant stage leaf rust resistance in bread wheat (Triticum aestivum L.).
Sign Up to like & getrecommendations! Published in 2022 at "Heredity"
DOI: 10.1038/s41437-022-00525-1
Abstract: Leaf rust is one of the important diseases limiting global wheat production and productivity. To identify quantitative trait nucleotides (QTNs) or genomic regions associated with seedling and adult plant leaf rust resistance, multilocus genome-wide association… read more here.
Keywords: genomic regions; leaf rust; wheat; resistance ... See more keywords
Genome-wide scan highlights the role of candidate genes on phenotypic plasticity for age at first calving in Nellore heifers
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63516-4
Abstract: Age at first calving (AFC) plays an important role in the economic efficiency of beef cattle production. This trait can be affected by a combination of genetic and environmental factors, leading to physiological changes in… read more here.
Keywords: age first; genomic regions; first calving; role ... See more keywords
Identification of genomic regions for grain yield and yield stability and their epistatic interactions
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep41578
Abstract: The task of identifying genomic regions conferring yield stability is challenging in any crop and requires large experimental data sets in conjunction with complex analytical approaches. We report findings of a first attempt to identify… read more here.
Keywords: yield stability; grain yield; genomic regions; yield ... See more keywords
SEGCOND predicts putative transcriptional condensate-associated genomic regions by integrating multi-omics data
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac742
Abstract: Abstract Motivation The compartmentalization of biochemical reactions, involved in the activation of gene expression in the eukaryotic nucleus, leads to the formation of membraneless bodies through liquid–liquid phase separation. These formations, called transcriptional condensates, appear… read more here.
Keywords: predicts putative; segcond predicts; transcriptional condensates; genomic regions ... See more keywords
The systematic analysis of ultraconserved genomic regions in the budding yeast.
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btx751
Abstract: Motivation: In the evolution of species, a kind of special sequences, termed ultraconserved sequences (UCSs), have been inherited without any change, which strongly suggests those sequences should be crucial for the species to survive or… read more here.
Keywords: budding yeast; analysis ultraconserved; regions budding; ultraconserved genomic ... See more keywords
Association rule mining to identify transcription factor interactions in genomic regions
Sign Up to like & getrecommendations! Published in 2020 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz687
Abstract: MOTIVATION Genome regulatory networks have different layers and ways to modulate cellular processes, such as cell differentiation, proliferation and adaptation to external stimuli. Transcription factors and other chromatin associated proteins act as combinatorial protein complexes… read more here.
Keywords: transcription; index; genomic regions; association ... See more keywords