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Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1699
Abstract: In HIV-1 infected cells, full-length viral genomic RNA (gRNA) is selectively packaged by the HIV-1 Gag protein despite a vast excess of spliced viral and host RNAs. The mechanism of this selective packaging is incompletely…
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Keywords:
psi rna;
gag;
rna;
genomic rna ... See more keywords
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Published in 2022 at "International Journal of Infectious Diseases"
DOI: 10.1016/j.ijid.2021.12.058
Abstract: Purpose As experienced by many countries, Sri Lanka is currently experiencing a large COVID-19 outbreak, with over 90 cases/one million population. The previous outbreak, which was due to the B.1.411 virus (Sri Lankan lineage) resulted…
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Keywords:
expression;
sars cov;
genomic rna;
lineage ... See more keywords
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Published in 2017 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2016.12.018
Abstract: Tospoviruses (genus Tospovirus, family Bunyaviridae) are responsible for major losses in an extensive range of crops worldwide. New species of these single-stranded, ambisense RNA viruses regularly emerge and have been shown to maintain heterogeneous populations…
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Keywords:
tospovirus;
genomic rna;
rna;
genome segments ... See more keywords
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Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac202
Abstract: Abstract During packaging in positive-sense single-stranded RNA (+ssRNA) viruses, coat proteins (CPs) interact directly with multiple regions in genomic RNA (gRNA), but the underlying physicochemical principles remain unclear. Here we analyze the high-resolution cryo-EM structure…
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Keywords:
single stranded;
coat proteins;
genomic rna;
stranded rna ... See more keywords
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Published in 2021 at "Retrovirology"
DOI: 10.1186/s12977-021-00582-0
Abstract: Background During HIV-1 maturation, Gag and Gag-Pol polyproteins are proteolytically cleaved and the capsid protein polymerizes to form the honeycomb capsid lattice. HIV-1 integrase (IN) binds the viral genomic RNA (gRNA) and impairment of IN-gRNA…
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Keywords:
structural changes;
hiv;
genomic rna;
local structural ... See more keywords
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Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11080861
Abstract: Tuberose (Polianthes tuberosa) is an ornamental flowering crop of the Amaryllidaceae family. Tuberose mild mosaic virus (TuMMV) and tuberose mild mottle virus (TuMMoV), members of the genus Potyvirus, are ubiquitously distributed in most tuberose growing…
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Keywords:
genomic rna;
tummov;
tuberose mild;
complete genomic ... See more keywords
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Published in 2021 at "Viruses"
DOI: 10.3390/v13030520
Abstract: The life cycle of the hepatitis C virus (HCV) can be divided into several stages, including viral entry, protein translation, RNA replication, viral assembly, and release. HCV genomic RNA replication occurs in the replication organelles…
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Keywords:
rna replication;
hcv genomic;
genomic rna;
replication complex ... See more keywords
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Published in 2021 at "Viruses"
DOI: 10.3390/v13050903
Abstract: Retroviruses are unique in that they package their RNA genomes as non-covalently linked dimers. Failure to dimerize their genomes results in decreased infectivity and reduced packaging of genomic RNA into virus particles. Two models of…
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Keywords:
genomic rna;
rna dimerization;
rna;
virus ... See more keywords
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Published in 2022 at "Viruses"
DOI: 10.3390/v14051094
Abstract: Two non-covalently linked copies of the retrovirus genome are specifically recruited to the site of virus particle assembly and packaged into released particles. Retroviral RNA packaging requires RNA export of the unspliced genomic RNA from…
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Keywords:
genomic rna;
human retrovirus;
rna;
retrovirus genomic ... See more keywords
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Published in 2022 at "Viruses"
DOI: 10.3390/v14091962
Abstract: Replication proteins of tobacco mosaic virus (TMV), a positive-sense RNA virus, co-translationally bind to a 5′-proximal ~70-nucleotide (nt) region of the genomic RNA, referred to as the nuclease-resistant (NR) region for replication template selection. Therefore,…
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Keywords:
genomic rna;
replication;
rna;
mosaic virus ... See more keywords
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Published in 2022 at "Viruses"
DOI: 10.3390/v14122606
Abstract: Alphaviruses must interact efficiently with two distinct host environments in order to replicate and transmit between vertebrate and mosquito hosts. Some host-origin-dependent differences in virus particle composition that appear to facilitate the transmission cycle are…
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Keywords:
genomic rna;
replication;
rna;
host dependent ... See more keywords