Cost-effectiveness of Population-Wide Genomic Screening for Hereditary Breast and Ovarian Cancer in the United States
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.22874
Abstract: Key Points Question Is it cost-effective to implement population-wide genomic screening for hereditary breast and ovarian cancer (HBOC)? Findings This decision analytical model study found that genomic screening for HBOC among unselected women may be… read more here.
Keywords: genomic screening; screening; screening hereditary; population wide ... See more keywords
Do research participants share genomic screening results with family members?
Sign Up to like & getrecommendations! Published in 2021 at "Journal of genetic counseling"
DOI: 10.1002/jgc4.1511
Abstract: The public health impact of genomic screening can be enhanced by cascade testing. However, cascade testing depends on communication of results to family members. While the barriers and facilitators of family communication have been researched… read more here.
Keywords: genomic screening; screening; family members; screening results ... See more keywords
Experiences of adolescents and their parents after receiving adolescents' genomic screening results.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of genetic counseling"
DOI: 10.1002/jgc4.1528
Abstract: There has been considerable debate over whether adolescents should have the opportunity to learn genetic information about adult-onset disease risk and carrier status without a clinical indication. Adolescents face increasing opportunities to learn more about… read more here.
Keywords: genomic screening; adolescents parents; receiving adolescents; experiences adolescents ... See more keywords
Genomic Screening for Malignant Hyperthermia Susceptibility
Sign Up to like & getrecommendations! Published in 2020 at "Anesthesiology"
DOI: 10.1097/aln.0000000000003547
Abstract: It is timely to consider the utility and practicability of screening for malignant hyperthermia susceptibility using genomic testing. Here the authors pose a simple, but bold question: what would it take to end deaths from… read more here.
Keywords: screening malignant; malignant hyperthermia; hyperthermia; genomic screening ... See more keywords
Genomic screening of Fabry disease in young stroke patients: the Taiwan experience and a review of the literature
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neurology"
DOI: 10.1111/ene.13775
Abstract: Fabry disease is an X‐linked disease, and enzyme‐based screening methods are not suitable for female patients. read more here.
Keywords: genomic screening; screening fabry; disease young; fabry disease ... See more keywords
Integrating Genomic Screening into Primary Care: Provider Experiences Caring for Latino Patients at a Community-Based Health Center
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Primary Care & Community Health"
DOI: 10.1177/21501327211000242
Abstract: Introduction: Minority communities have had limited access to advances in genomic medicine. Mayo Clinic and Mountain Park Health Center, a Federally Qualified Health Center in Phoenix, Arizona, partnered to assess the feasibility of offering genomic… read more here.
Keywords: medicine; genomic screening; health; care ... See more keywords
Assessing the implications of positive genomic screening results
Sign Up to like & getrecommendations! Published in 2020 at "Personalized Medicine"
DOI: 10.2217/pme-2019-0067
Abstract: Aim: Before population screening of ‘healthy’ individuals is widely adopted, it is important to consider the harms and benefits of receiving positive results and how harms and benefits may differ by age. Subjects & methods:… read more here.
Keywords: positive results; genomic screening; implications positive; assessing implications ... See more keywords
Parental Guidance Suggested: Engaging Parents as Partners in Research Studies of Genomic Screening for a Pediatric Population
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.867030
Abstract: Recent advances in genomic sequencing and genomic medicine are reshaping the landscape of clinical care. As a screening modality, genetic sequencing has the potential to dramatically expand the clinical utility of newborn screening (NBS), though… read more here.
Keywords: suggested engaging; parental guidance; guidance suggested; genomic screening ... See more keywords
Population genomic screening: Ethical considerations to guide age at implementation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.899648
Abstract: Currently, most genetic testing involves next generation sequencing or panel testing, indicating future population-based screening will involve simultaneous testing for multiple disease risks (called here “panel testing”). Genomic screening typically focuses on single or groups… read more here.
Keywords: age majority; age; panel; genomic screening ... See more keywords
Healthcare Utilization and Costs after Receiving a Positive BRCA1/2 Result from a Genomic Screening Program
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm10010007
Abstract: Population genomic screening has been demonstrated to detect at-risk individuals who would not be clinically identified otherwise. However, there are concerns about the increased utilization of unnecessary services and the associated increase in costs. The… read more here.
Keywords: screening program; utilization; genomic screening; brca1 ... See more keywords
Understanding the Patient Experience of Receiving Clinically Actionable Genetic Results from the MyCode Community Health Initiative, a Population-Based Genomic Screening Initiative
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12091511
Abstract: Understanding unselected individuals’ experiences receiving genetic results through population genomic screening is critical to advancing clinical utility and improving population health. We conducted qualitative interviews with individuals who received clinically actionable genetic results via the… read more here.
Keywords: clinically actionable; receiving clinically; genetic results; genomic screening ... See more keywords