Genomic Signatures Among Acanthamoeba polyphaga Entoorganisms Unveil Evidence of Coevolution
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Evolution"
DOI: 10.1007/s00239-018-9877-1
Abstract: The definition of a genomic signature (GS) is “the total net response to selective pressure”. Recent isolation and sequencing of naturally occurring organisms, hereby named entoorganisms, within Acanthamoeba polyphaga, raised the hypothesis of a common… read more here.
Keywords: entoorganisms unveil; polyphaga entoorganisms; acanthamoeba polyphaga; signatures among ... See more keywords
Population genomic signatures of the oriental fruit moth related to the Pleistocene climates
Sign Up to like & getrecommendations! Published in 2022 at "Communications Biology"
DOI: 10.1038/s42003-022-03097-2
Abstract: The Quaternary climatic oscillations are expected to have had strong impacts on the evolution of species. Although legacies of the Quaternary climates on population processes have been widely identified in diverse groups of species, adaptive… read more here.
Keywords: fruit moth; climates population; genomic signatures; oriental fruit ... See more keywords
Genomic Signatures of Honey Bee Association in an Acetic Acid Symbiont
Sign Up to like & getrecommendations! Published in 2020 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evaa183
Abstract: Abstract Recent declines in the health of the honey bee have startled researchers and lay people alike as honey bees are agriculture’s most important pollinator. Honey bees are important pollinators of many major crops and… read more here.
Keywords: bee association; honey; genomic signatures; honey bee ... See more keywords
Genomic Signatures of Divergent Ecological Strategies in a Recent Radiation of Neotropical Wild Cats
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac117
Abstract: Abstract Ecological differentiation among diverging species is an important component of the evolutionary process and can be investigated in rapid and recent radiations. Here, we use whole genome sequences of five species from the genus… read more here.
Keywords: signatures divergent; recent radiation; strategies recent; ecological strategies ... See more keywords
Genomic signatures of introgression between commercial and native bumblebees, Bombus terrestris, in western Iberian Peninsula—Implications for conservation and trade regulation
Sign Up to like & getrecommendations! Published in 2019 at "Evolutionary Applications"
DOI: 10.1111/eva.12732
Abstract: Human‐mediated introductions of species may have profound impacts on native ecosystems. One potential impact with largely unforeseen consequences is the potential admixture of introduced with autochthonous species through hybridization. Throughout the world, bumblebees have been… read more here.
Keywords: introgression commercial; bombus terrestris; signatures introgression; commercial bumblebees ... See more keywords
Genomic signatures of selection in bats surviving white-nose syndrome.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular ecology"
DOI: 10.1111/mec.15813
Abstract: Rapid evolution of advantageous traits following abrupt environmental change can help populations recover from demographic decline. However, for many introduced diseases affecting longer-lived, slower reproducing hosts, mortality is likely to outpace the acquisition of adaptive… read more here.
Keywords: signatures selection; selection bats; selection; nose syndrome ... See more keywords
Genomic signatures in the coral holobiont reveal host adaptations driven by Holocene climate change and reef specific symbionts
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc6318
Abstract: Genomes of 150 coral colonies reveal evolutionary processes related to past climatic change on the Great Barrier Reef. Genetic signatures caused by demographic and adaptive processes during past climatic shifts can inform predictions of species’… read more here.
Keywords: change; climate change; host; genomic signatures ... See more keywords
Genomic signatures of the unjamming transition in compressed human bronchial epithelial cells
Sign Up to like & getrecommendations! Published in 2021 at "Science Advances"
DOI: 10.1126/sciadv.abf1088
Abstract: Temporal RNA-seq data reveal genomic signatures of the unjamming transition in compressed human bronchial epithelial cells. Epithelial tissue can transition from a jammed, solid-like, quiescent phase to an unjammed, fluid-like, migratory phase, but the underlying… read more here.
Keywords: unjamming transition; epithelial cells; transition; bronchial epithelial ... See more keywords
Convergent genomic signatures of local adaptation across a continental-scale environmental gradient
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DOI: 10.1126/sciadv.add0560
Abstract: Convergent local adaptation offers a glimpse into the role of constraint and stochasticity in adaptive evolution, in particular the extent to which similar genetic mechanisms drive adaptation to common selective forces. Here, we investigated the… read more here.
Keywords: adaptation; local adaptation; convergent genomic; signatures local ... See more keywords
Genomic Signatures Predict the Immunogenicity of BRCA-Deficient Breast Cancer
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DOI: 10.1158/1078-0432.ccr-18-0468
Abstract: Purpose: Breast cancers with BRCA1/2 alterations have a relatively high mutational load, suggesting that immune checkpoint blockade may be a potential treatment option. However, the degree of immune cell infiltration varies widely, and molecular features… read more here.
Keywords: cancer; breast cancers; breast; predict immunogenicity ... See more keywords
Abstract 6778: Spatial analysis of genomic signatures on colorectal cancer pathogenesis using the GeoMx® Digital Spatial Profiler
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-6778
Abstract: Background: The development of colorectal cancer (CRC) is a complex process, involving multiple sequential molecular aberrations that contribute to disease progression. Understanding the immunopathogenesis of CRC particularly within the spatial context of tumor microenvironment (TME)… read more here.
Keywords: geomx digital; analysis; colorectal cancer; digital spatial ... See more keywords