Genomic Variation and Pharmacokinetics in Old Age: A Quantitative Review of Age‐ vs. Genotype‐Related Differences
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.1057
Abstract: Older persons may particularly benefit from pharmacogenetic diagnostics, but there is little clinical evidence on that question. We quantitatively analyzed the effects of age and genotype in drugs with consensus on a therapeutically relevant impact… read more here.
Keywords: age genotype; age; variation pharmacokinetics; genomic variation ... See more keywords
Genomic variation among populations provides insight into the causes of metacommunity survival.
Sign Up to like & getrecommendations! Published in 2020 at "Ecology"
DOI: 10.1002/ecy.3182
Abstract: Predators and prey interact at small spatial scales, but during their lifetime disperse at much larger spatial scales. Trophic metacommunity theory proposes that dispersal is a critical processes that determines food webs structure at small… read more here.
Keywords: among populations; populations provides; metacommunity; provides insight ... See more keywords
Pattern of genomic variation in SARS-CoV-2 (COVID-19) suggests restricted nonrandom changes: Analysis using Shewhart control charts
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biosciences"
DOI: 10.1007/s12038-020-00131-5
Abstract: SARS-CoV-2 is a member of the Coronavirus family which recently originated from the Wuhan province of China and spread very rapidly through the world infecting more than 4 million people. In the past, other Coronaviruses… read more here.
Keywords: shewhart control; variation sars; analysis; pattern genomic ... See more keywords
Regulatory Genomic Variation In The Developing Brain: Relevance To Neuropsychiatric Phenotypes
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.06.137
Abstract: Abstract Epigenetic processes play a key role in orchestrating transcriptional regulation during the development of the human central nervous system. We have quantified dynamic changes in DNA methylation (5mC) and DNA hydroxymethylation (5hmC) occurring during… read more here.
Keywords: fetal brain; variation; regulatory genomic; variation developing ... See more keywords
The HuangZaoSi Maize Genome Provides Insights into Genomic Variation and Improvement History of Maize.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular plant"
DOI: 10.1016/j.molp.2019.02.009
Abstract: Maize is a globally important crop that was a classic model plant for genetic studies. Here, we report a 2.2 Gb draft genome sequence of an elite maize line, HuangZaoSi (HZS). Hybrids bred from HZS-improved lines… read more here.
Keywords: hzs; maize genome; history; variation improvement ... See more keywords
Genomic Variation and Recent Population Histories of Spotted (Strix occidentalis) and Barred (Strix varia) Owls
Sign Up to like & getrecommendations! Published in 2021 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evab066
Abstract: Abstract Spotted owls (SOs, Strix occidentalis) are a flagship species inhabiting old-growth forests in western North America. In recent decades, their populations have declined due to ongoing reductions in suitable habitat caused by logging, wildfires,… read more here.
Keywords: strix occidentalis; strix varia; variation recent; north america ... See more keywords
Genomic patterns of diversity and divergence of two introduced salmonid species in Patagonia, South America
Sign Up to like & getrecommendations! Published in 2017 at "Evolutionary Applications"
DOI: 10.1111/eva.12464
Abstract: Invasive species have become widespread in aquatic environments throughout the world, yet there are few studies that have examined genomic variation of multiple introduced species in newly colonized environments. In this study, we contrast genomic… read more here.
Keywords: salmonid species; diversity; native range; south america ... See more keywords
Spatiotemporally explicit demographic modelling supports a joint effect of historical barriers to dispersal and contemporary landscape composition on structuring genomic variation in a red‐listed grasshopper
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Ecology"
DOI: 10.1111/mec.15086
Abstract: Inferring the processes underlying spatial patterns of genomic variation is fundamental to understand how organisms interact with landscape heterogeneity and to identify the factors determining species distributional shifts. Here, we use genomic data (restriction site‐associated… read more here.
Keywords: variation; barriers dispersal; spatiotemporally explicit; landscape composition ... See more keywords
Complex signatures of genomic variation of two non-model marine species in a homogeneous environment
Sign Up to like & getrecommendations! Published in 2018 at "BMC Genomics"
DOI: 10.1186/s12864-018-4721-y
Abstract: BackgroundGenomic tools are increasingly being used on non-model organisms to provide insights into population structure and variability, including signals of selection. However, most studies are carried out in regions with distinct environmental gradients or across… read more here.
Keywords: variation; outlier loci; homogeneous environment; non model ... See more keywords
Genomic variation among closely related Vibrio alginolyticus strains is located on mobile genetic elements
Sign Up to like & getrecommendations! Published in 2020 at "BMC Genomics"
DOI: 10.1186/s12864-020-6735-5
Abstract: Species of the genus Vibrio, one of the most diverse bacteria genera, have undergone niche adaptation followed by clonal expansion. Niche adaptation and ultimately the formation of ecotypes and speciation in this genus has been… read more here.
Keywords: variation; vibrio; alginolyticus strains; mobile genetic ... See more keywords
Genomic variation and biogeography of Antarctic haloarchaea
Sign Up to like & getrecommendations! Published in 2018 at "Microbiome"
DOI: 10.1186/s40168-018-0495-3
Abstract: BackgroundThe genomes of halophilic archaea (haloarchaea) often comprise multiple replicons. Genomic variation in haloarchaea has been linked to viral infection pressure and, in the case of Antarctic communities, can be caused by intergenera gene exchange.… read more here.
Keywords: variation; variation biogeography; haloarchaea; genomic variation ... See more keywords