Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.04.046
Abstract: Structural variations (SVs) and gene copy number variations (gCNVs) have contributed to crop evolution, domestication, and improvement. Here, we assembled 31 high-quality genomes of genetically diverse rice accessions. Coupling with two existing assemblies, we developed… read more here.
Keywords: rice; diverse rice; genomic variations; pan genome ... See more keywords
Novel correlative analysis identifies multiple genomic variations impacting ASD with macrocephaly.
Sign Up to like & getrecommendations! Published in 2022 at "Human molecular genetics"
DOI: 10.1093/hmg/ddac300
Abstract: Autism spectrum disorders (ASD) display both phenotypic and genetic heterogeneity, impeding the understanding of ASD and development of effective means of diagnosis and potential treatments. Genes affected by genomic variations for ASD converge in dozens… read more here.
Keywords: asd macrocephaly; etiology; analysis; genomic variations ... See more keywords
Genomic Variations in the Structural Proteins of SARS-CoV-2 and Their Deleterious Impact on Pathogenesis: A Comparative Genomics Approach
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.765039
Abstract: A continual rise in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection causing coronavirus disease (COVID-19) has become a global threat. The main problem comes when SARS-CoV-2 gets mutated with the rising infection and becomes more… read more here.
Keywords: comparative genomics; structural proteins; genomic variations; proteins sars ... See more keywords
Evolutionary Trajectories of Primary and Metastatic Pancreatic Neuroendocrine Tumors Based on Genomic Variations
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13091588
Abstract: Liver metastases are common in pancreatic neuroendocrine tumors (PanNETs) patients and they are considered a poor prognostic marker. This study aims to analyze the spatiotemporal patterns of genomic variations between primary and metastatic tumors, and… read more here.
Keywords: pancreatic neuroendocrine; neuroendocrine tumors; primary metastatic; genomic variations ... See more keywords