A disease network-based deep learning approach for characterizing melanoma.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of cancer"
DOI: 10.1002/ijc.33860
Abstract: Multiple types of genomic variations are present in cutaneous melanoma and some of the genomic features may have an impact on the prognosis of the disease. The access to genomics data via public repositories such… read more here.
Keywords: melanoma; network; deep learning; disease ... See more keywords
Applying Machine Learning for Integration of Multi-Modal Genomics Data and Imaging Data to Quantify Heterogeneity in Tumour Tissues
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0826-5_10
Abstract: With rapid advances in experimental instruments and protocols, imaging and sequencing data are being generated at an unprecedented rate contributing significantly to the current and coming big biomedical data. Meanwhile, unprecedented advances in computational infrastructure… read more here.
Keywords: imaging data; machine learning; applying machine; integration ... See more keywords
BRGenomics for analyzing high resolution genomics data in R.
Sign Up to like & getrecommendations! Published in 2023 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btad331
Abstract: SUMMARY I present here the R/Bioconductor package BRGenomics, which provides fast and flexible methods for post-alignment processing and analysis of high resolution genomics data within an interactive R environment. Utilizing GenomicRanges and other core Bioconductor… read more here.
Keywords: brgenomics analyzing; resolution genomics; bioconductor; genomics data ... See more keywords
Gosling: A Grammar-based Toolkit for Scalable and Interactive Genomics Data Visualization
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Visualization and Computer Graphics"
DOI: 10.1109/tvcg.2021.3114876
Abstract: The combination of diverse data types and analysis tasks in genomics has resulted in the development of a wide range of visualization techniques and tools. However, most existing tools are tailored to a specific problem… read more here.
Keywords: data visualization; scalable interactive; gosling grammar; genomics data ... See more keywords
Novel vaccine design based on genomics data analysis: A review
Sign Up to like & getrecommendations! Published in 2020 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.12986
Abstract: Modification of pathogenic strains with the passage of time is responsible for evolution in the timeline of vaccine development for last 30 years. Recent advancements in computational vaccinology on the one hand and genome sequencing… read more here.
Keywords: novel vaccine; vaccine design; review; vaccine ... See more keywords
Value of collaboration among multidomain experts in analysis of high-throughput genomics data.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer research"
DOI: 10.1158/0008-5472.can-19-0769
Abstract: The recent explosion and ease of access to large-scale genomics data is intriguing. However, serious obstacles exist to the optimal management of the entire spectrum from data production in the laboratory through bioinformatic analysis to… read more here.
Keywords: among multidomain; analysis; multidomain experts; genomics data ... See more keywords
Genomics and data science: an application within an umbrella
Sign Up to like & getrecommendations! Published in 2019 at "Genome Biology"
DOI: 10.1186/s13059-019-1724-1
Abstract: Data science allows the extraction of practical insights from large-scale data. Here, we contextualize it as an umbrella term, encompassing several disparate subdomains. We focus on how genomics fits as a specific application subdomain, in… read more here.
Keywords: science; science application; application within; data science ... See more keywords
A simple in silico approach to generate gene-expression profiles from subsets of cancer genomics data.
Sign Up to like & getrecommendations! Published in 2019 at "BioTechniques"
DOI: 10.2144/btn-2018-0179
Abstract: In biomedical research, large-scale profiling of gene expression has become routine and offers a valuable means to evaluate changes in onset and progression of diseases, in particular cancer. An overwhelming amount of cancer genomics data… read more here.
Keywords: cancer; cancer genomics; gene expression; genomics data ... See more keywords
Network Control Models With Personalized Genomics Data for Understanding Tumor Heterogeneity in Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.891676
Abstract: Due to rapid development of high-throughput sequencing and biotechnology, it has brought new opportunities and challenges in developing efficient computational methods for exploring personalized genomics data of cancer patients. Because of the high-dimension and small… read more here.
Keywords: network; network control; genomics data; personalized genomics ... See more keywords